SCHEMBL6653689

SCHEMBL6653689

N#Cc1ccc(Nc2c(F)c3c(c(F)c2Nc2ccc(C#N)c(C#N)c2)C(=O)c2ccccc2C3=O)cc1C#N

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP8 P40818 1/20 0.45
USP7 Q93009 1/20 0.45
ABCG2 Q9UNQ0 2/20 0.38
TAS2R14 Q9NYV8 1/20 0.38
MAP3K8 P41279 2/20 0.36
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
P2RY4 P51582 2/20 0.36
PRKCQ Q04759 2/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
GRM5 P41594 1/20 0.34
DHODH Q02127 1/20 0.34
CASP3 P42574 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
SLC22A12 Q96S37 3/20 0.34
GRM4 Q14833 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21816981 0.95 USP8 (0.43) USP8USP7ABCG2TAS2R14MAP3K8
SCHEMBL6650707 0.88 SLC22A12 (0.47) USP8USP7MAP3K8CYP11B1CYP11B2
SCHEMBL29502811 0.82 SRC (0.40) USP8USP7EGFR
SCHEMBL22283398 0.82 SRC (0.40) USP8USP7EGFR
SCHEMBL6652697 0.82 MAPT (0.44) ABCG2MEN1MAPTKMT2ADHODH
SCHEMBL29460867 0.78 SLC22A12 (0.43) USP8USP7MAP3K8CYP11B2SLC22A12
SCHEMBL6654379 0.77 MAPT (0.42) ABCG2MEN1MAPTKMT2ADHODH
SCHEMBL21817082 0.76 STK10 (0.48) ABCG2GRM5SLC22A12
SCHEMBL21816966 0.76 MAPT (0.54) P2RY4MEN1MAPTKMT2ADHODH
SCHEMBL6652975 0.74 MAPT (0.41) ABCG2MEN1MAPTKMT2ACASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0833203-B1 Anthraquinone compounds NIPPON CATALYTIC CHEM IND (JP) 2004-06-16 EP disclosed
US-5968688-A RESINS AND DYES FOR COLOR FILTERS NIPPON SHOKUBAI CO., LTD. (JP) 1999-10-19 US disclosed
EP-0833203-A1 Color filter grade photosensitive resin coloring composition, and color filter using the same NIPPON SHOKUBAI CO., LTD. (JP) 1998-04-01 EP disclosed