SCHEMBL665387

SCHEMBL665387

CCCCOCC(CC)(COCCCC)COCCCC

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
THRB P10828 2/20 0.42
CES1 P23141 1/20 0.42
CYP3A4 P08684 2/20 0.38
ADRB2 P07550 1/20 0.38
ADRB1 P08588 1/20 0.38
ADRB3 P13945 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
HPGD P15428 1/20 0.37
MEN1 O00255 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
MAPT P10636 1/20 0.34
CES2 O00748 2/20 0.33
ALDH1A1 P00352 3/20 0.32
LTA4H P09960 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18306217 0.95 TSHR (0.44) TSHRTHRBCES1CYP3A4ADRB2
SCHEMBL10172485 0.95 TSHR (0.44) TSHRTHRBCES1CYP3A4ADRB2
SCHEMBL13165932 0.90 CES1 (0.53) TSHRTHRBCES1MEN1HTT
SCHEMBL4879022 0.90 CES1 (0.53) TSHRTHRBCES1MEN1HTT
SCHEMBL15412040 0.90 CES1 (0.53) TSHRTHRBCES1MEN1HTT
SCHEMBL15412436 0.90 CES1 (0.53) TSHRTHRBCES1MEN1HTT
SCHEMBL11152951 0.90 CES1 (0.53) TSHRTHRBCES1MEN1HTT
SCHEMBL278799 0.89 TSHR (0.48) TSHRTHRBCES1CYP3A4ADRB2
SCHEMBL26711992 0.89 CYP3A4 (0.43) TSHRTHRBCES1CYP3A4ADRB2
SCHEMBL18378988 0.86 TSHR (0.46) TSHRTHRBCES1CYP3A4ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4074807-B1 COMPOSITIONS COMPRISING A FLUOROOLEFIN CHEMOURS CO FC LLC (US) 2025-07-09 EP disclosed
EP-3543310-B2 COMPOSITIONS COMPRISING HFC-1234YF AND HFC-32 CHEMOURS CO FC LLC (US) 2024-07-03 EP disclosed
EP-3299435-B1 METHOD OF PREPARING A COMPOSITION COMPRISING HFC-1234YF CHEMOURS CO FC LLC (US) 2024-06-26 EP disclosed
EP-3309233-B2 COMPOSITIONS COMPRISING HFC-1234YF AND HFC-152A CHEMOURS CO FC LLC (US) 2024-02-21 EP disclosed
EP-2749623-B2 Method for replacing a high GWP refrigerant in a refrigeration, air-conditioning, or heat pump apparatus CHEMOURS CO FC LLC (US) 2024-02-21 EP disclosed
CN-113845884-B Compositions comprising fluoroolefins 科慕埃弗西有限公司 2024-02-02 CN disclosed
CN-113549426-B Compositions comprising fluoroolefins 科慕埃弗西有限公司 2023-11-14 CN disclosed
US-20230265330-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN THE CHEMOURS COMPANY FC, LLC (US) 2023-08-24 US disclosed
US-11674067-B2 Compositions comprising a fluoroolefin THE CHEMOURS COMPANY FC, LLC (US) 2023-06-13 US disclosed
US-20220389297-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN THE CHEMOURS COMPANY FC, LLC (US) 2022-12-08 US disclosed
US-20040099838-A1 Refrigerant compositions comprising performance enhancing additives E. I. DU PONT DE NEMOURS AND COMPANY 2004-05-27 US disclosed
US-20040041122-A1 Fluorocarbon, oxygenated and non-oxygenated lubricant, and compatibilizer composition, and method for replacing refrigeration composition in a refrigeration system E.I. DU PONT DE NEMOURS AND COMPANY 2004-03-04 US disclosed
WO-2002046328-A9 REFRIGERANT COMPOSITIONS CONTAINING A COMPATIBILIZER DU PONT (US) 2004-03-04 WO disclosed
WO-2004015042-A2 REFRIGERANT COMPOSITIONS COMPRISING PERFORMANCE ENHANCING ADDITIVES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2004-02-19 WO disclosed
WO-2003104364-A1 FLUOROCARBON, OXYGENATED AND NON-OXYGENATED LUBRICANT, AND COMPATIBILIZER COMPOSITION, AND METHOD FOR REPLACING REFRIGERATION COMPOSITION IN A REFRIGERATION SYSTEM E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-12-18 WO disclosed
US-20030209688-A1 Refrigerant compositions containing a compatibilizer E. I. DU PONT DE NEMOURS AND COMPANY 2003-11-13 US disclosed
EP-1341868-A2 REFRIGERANT COMPOSITIONS CONTAINING A COMPATIBILIZER E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-09-10 EP disclosed
WO-2003050200-A1 REFRIGERANT COMPOSITIONS CONTAINING A COMPATIBILIZER AND USE THEROF IN A COMPRESSION REFRIGERATION APPARATUS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-06-19 WO disclosed
US-20030034477-A1 Refrigerant compositions containing a compatibilizer E. I. DU PONT DE NEMOURS AND COMPANY 2003-02-20 US disclosed
WO-2002046328-A2 REFRIGERANT COMPOSITIONS CONTAINING A COMPATIBILIZER E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-06-13 WO disclosed