Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18378988 | 0.97 | TSHR (0.46) | TSHRCES1ADRB2ADRB1ADRB3 | |
| SCHEMBL19792791 | 0.95 | TSHR (0.50) | TSHRCES1ADRB2ADRB1ADRB3 | |
| SCHEMBL17775385 | 0.95 | CES1 (0.52) | TSHRCES1ADRB2ADRB1ADRB3 | |
| SCHEMBL278793 | 0.92 | TSHR (0.42) | TSHRCES1ADRB2ADRB1ADRB3 | |
| SCHEMBL278852 | 0.92 | TSHR (0.42) | TSHRCES1ADRB2ADRB1ADRB3 | |
| SCHEMBL278935 | 0.92 | TSHR (0.42) | TSHRCES1ADRB2ADRB1ADRB3 | |
| SCHEMBL4875783 | 0.89 | CES1 (0.57) | TSHRCES1THRBMEN1HTT | |
| SCHEMBL665387 | 0.89 | TSHR (0.44) | TSHRCES1ADRB2ADRB1ADRB3 | |
| SCHEMBL11149666 | 0.89 | CES1 (0.57) | TSHRCES1THRBMEN1HTT | |
| SCHEMBL10172485 | 0.89 | TSHR (0.44) | TSHRCES1ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170114245-A1 | DISPERSION COMPOSITION, CURABLE COMPOSITION USING THE SAME, TRANSPARENT FILM, MICROLENS AND SOLID-STATE IMAGING DEVICE | FUJIFILM CORPORATION (JP) | 2017-04-27 | — | — | US | disclosed |
| US-9517278-B2 | Compound and photoacoustic imaging contrast medium containing the compound | CANON KABUSHIKI KAISHA (JP) | 2016-12-13 | — | — | US | disclosed |
| US-9359392-B2 | Dendrimer scaffolds for pharmaceutical use | VICTORIA LINK LIMITED (NZ) | 2016-06-07 | — | — | US | disclosed |
| US-20160145287-A2 | Dendrimer Scaffolds for Pharmaceutical Use | VICTORIA LINK LIMITED (NZ) | 2016-05-26 | — | — | US | disclosed |
| US-20150225439-A1 | Dendrimer Scaffolds for Pharmaceutical Use | VICTORIA LINK LTD (NZ) | 2015-08-13 | — | — | US | disclosed |
| US-20150165071-A1 | COMPOUND AND PHOTOACOUSTIC IMAGING CONTRAST MEDIUM CONTAINING THE COMPOUND | CANON KABUSHIKI KAISHA (JP) | 2015-06-18 | — | — | US | disclosed |
| US-8133707-B2 | Methods of preparing activated polymers having alpha nitrogen groups | ENZON PHARMACEUTICALS, INC. (US) | 2012-03-13 | — | — | US | disclosed |
| US-20070166808-A1 | Methods of preparing activated polymers having alpha nitrogen groups | BELROSE PHARMA INC. | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150225439-A1 | Dendrimer Scaffolds for Pharmaceutical Use | CD38, ADCYAP1R1, PIGO | TSHR 4706/4885CES1 3230/4885ADRB2 1581/4885 |
| US-20160145287-A2 | Dendrimer Scaffolds for Pharmaceutical Use | CD38, ADCYAP1R1, PIGO | TSHR 4706/4885CES1 3230/4885ADRB2 1581/4885 |
| US-20150165071-A1 | COMPOUND AND PHOTOACOUSTIC IMAGING CONTRAST MEDIUM CONTAINING THE COMPOUND | CLTB, PAM, CLTA | TSHR 4220/4885CES1 3750/4885ADRB2 2727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.