Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.45 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.45 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.45 |
| ▸ | SSTR4 | P31391 | 4/20 | 0.43 |
| ▸ | NAAA | Q02083 | 3/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653458 | 1.00 | GNAI3 (0.45) | GNAI3GNAO1GNAI1SSTR4NAAA | |
| SCHEMBL6651713 | 1.00 | GNAI3 (0.45) | GNAI3GNAO1GNAI1SSTR4NAAA | |
| SCHEMBL10614976 | 0.81 | GNAI3 (0.40) | GNAI3GNAO1GNAI1SSTR4NAAA | |
| SCHEMBL11513774 | 0.81 | GNAI3 (0.40) | GNAI3GNAO1GNAI1SSTR4NAAA | |
| SCHEMBL2982117 | 0.81 | GNAI3 (0.40) | GNAI3GNAO1GNAI1SSTR4NAAA | |
| SCHEMBL25271185 | 0.81 | GNAI3 (0.40) | GNAI3GNAO1GNAI1SSTR4NAAA | |
| SCHEMBL474078 | 0.81 | GNAI3 (0.40) | GNAI3GNAO1GNAI1SSTR4NAAA | |
| SCHEMBL25021727 | 0.81 | GNAI3 (0.54) | GNAI3GNAO1GNAI1SSTR4NAAA | |
| SCHEMBL25023253 | 0.81 | GNAI3 (0.54) | GNAI3GNAO1GNAI1SSTR4NAAA | |
| SCHEMBL2720664 | 0.80 | SSTR4 (0.40) | GNAI3GNAO1GNAI1SSTR4NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425004-A1 | USE OF COMPOUNDS AS FUNCTIONAL ANTAGONISTS TO THE CENTRAL CANNABINOID RECEPTORS | Research & Innovation Soc. Coop. A R.L. (IT) | 2004-06-09 | — | — | EP | disclosed |
| WO-2003006007-A1 | USE OF COMPOUNDS AS FUNCTIONAL ANTAGONISTS TO THE CENTRAL CANNABINOID RECEPTORS | RESEARCH & INNOVATION SOC.COOP. A R.L. (IT) | 2003-01-23 | — | — | WO | disclosed |