SCHEMBL6654006

SCHEMBL6654006

CCC(=O)CCCO[Si](CC)(CC)CC

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6651752 0.94 TDP1 (0.35) TDP1ALDH1A1
SCHEMBL6654251 0.91 MAPT (0.35)
SCHEMBL6652592 0.88 MAPT (0.33)
SCHEMBL6648970 0.87 TDP1 (0.39) TDP1ALDH1A1
SCHEMBL6649255 0.86 MAPT (0.36) ALDH1A1
SCHEMBL6649477 0.81 ALDH1A1 (0.38) TDP1ALDH1A1
SCHEMBL6651140 0.81 TDP1 (0.38) TDP1ALDH1A1
SCHEMBL6650721 0.78 TDP1 (0.30) TDP1
SCHEMBL6651710 0.78 MAPT (0.41) ALDH1A1
SCHEMBL6649876 0.75 PAOX (0.40) TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6534665-B1 Used for polymerization and copolymerization of olefins REPSOL QUIMICA S.A. (ES) 2003-03-18 US claimed
EP-1095944-B1 Single-carbon bridged bis cyclopentadienyl compounds and metallocene complexes thereof REPSOL QUIMICA SA (ES) 2004-03-17 EP disclosed
US-6534665-B1 Used for polymerization and copolymerization of olefins REPSOL QUIMICA S.A. (ES) 2003-03-18 US disclosed
EP-1095944-A1 Single-carbon bridged bis cyclopentadienyl compounds and metallocene complexes thereof REPSOL QUIMICA S.A. (ES) 2001-05-02 EP disclosed