Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ICMT | O60725 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6654519 | 1.00 | PPARG (0.48) | PPARGPPARAMAPTICMTGMNN | |
| SCHEMBL28035 | 0.85 | MAPT (0.60) | PPARGPPARAMAPTICMTGMNN | |
| SCHEMBL5604693 | 0.85 | MAPT (0.60) | PPARGPPARAMAPTICMTGMNN | |
| SCHEMBL28036 | 0.85 | MAPT (0.60) | PPARGPPARAMAPTICMTGMNN | |
| SCHEMBL15345638 | 0.84 | MAPT (0.62) | MAPTICMTGMNNTRPA1LMNA | |
| SCHEMBL18759162 | 0.83 | MAPT (0.51) | PPARGPPARAMAPTICMTGMNN | |
| SCHEMBL6654518 | 0.82 | MAPT (0.50) | PPARGPPARAMAPTICMTGMNN | |
| SCHEMBL5502025 | 0.80 | BACE1 (0.40) | PPARGPPARAMAPTPGRHTR1A | |
| SCHEMBL5823579 | 0.78 | ACHE (0.56) | PPARGPPARAMAPTPGRHTR1A | |
| SCHEMBL28432644 | 0.78 | PTGS1 (0.52) | PPARGPPARAMAPTPGRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0875501-B1 | Alkylenediamine derivative, anti-ulcer drug, and antibacterial drug | SHISEIDO CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| EP-0802196-B1 | Alkylenediamine derivatives as drugs for the treatment of ulcers and the inhibition of Helicobacter pylori | SHISEIDO CO LTD (JP) | 2001-08-29 | — | — | EP | disclosed |
| US-6043243-A | Pyrrolidine derivative, anti-ulcer drug, and antibacterial drug | SHISEIDO CO., LTD. (JP) | 2000-03-28 | — | — | US | disclosed |
| US-6001880-A | DISUBSTITUTED N-(2-DIALKYLAMINOETHYL)BENZAMIDE DERIVATIVES OF GIVEN FORMULA; ANTIBACTERIAL ACTIVITY AGAINST HELICOBACTER PYROLI, ADMINISTERING FOR THE PREVENTION OR CURE OF PEPTIC ULCERS | SHISEIDO CO., LTD. (JP) | 1999-12-14 | — | — | US | disclosed |
| US-5925667-A | INHIBITS GROWTH OF HELICOBACTER PYLORI | SHISEIDO CO., LTD. (JP) | 1999-07-20 | — | — | US | disclosed |
| EP-0875501-A2 | Alkylenediamine derivative, anti-ulcer drug, and antibacterial drug | SHISEIDO COMPANY LIMITED (JP) | 1998-11-04 | — | — | EP | disclosed |
| EP-0869118-A1 | Pyrrolidine derivative, anti-ulcer drug, and antibacterial drug | SHISEIDO COMPANY LIMITED (JP) | 1998-10-07 | — | — | EP | disclosed |
| US-5814634-A | PEPTIC ULCERS, GASTRIC ULCERS | SHISEIDO CO. LTD. (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0802196-A1 | Alkylenediamine derivative, antiulcer drug, and antibacterial drug | SHISEIDO COMPANY LIMITED (JP) | 1997-10-22 | — | — | EP | disclosed |