Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | STK17B | O94768 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 3/20 | 0.32 |
| ▸ | GSK3B | P49841 | 3/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511650 | 1.00 | MEN1 (0.35) | MEN1KMT2ASTK17BKDM4EMAPK1 | |
| SCHEMBL7649928 | 1.00 | MEN1 (0.35) | MEN1KMT2ASTK17BKDM4EMAPK1 | |
| SCHEMBL16382613 | 1.00 | MEN1 (0.35) | MEN1KMT2ASTK17BKDM4EMAPK1 | |
| SCHEMBL22057240 | 1.00 | MEN1 (0.35) | MEN1KMT2ASTK17BKDM4EMAPK1 | |
| SCHEMBL31738409 | 1.00 | MEN1 (0.35) | MEN1KMT2ASTK17BKDM4EMAPK1 | |
| SCHEMBL16378826 | 0.85 | KDM4E (0.34) | STK17BKDM4EMAPK1ATMACHE | |
| SCHEMBL18924580 | 0.83 | KDM4E (0.33) | MEN1KMT2ASTK17BKDM4EMAPK1 | |
| SCHEMBL7170811 | 0.82 | MEN1 (0.48) | MEN1KMT2ASTK17BKDM4EMAPK1 | |
| SCHEMBL5196943 | 0.81 | TYMS (0.40) | MEN1KMT2ASTK17BKDM4EMAPK1 | |
| SCHEMBL5196941 | 0.81 | TYMS (0.40) | MEN1KMT2ASTK17BKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1185505-B1 | METHOD OF PRODUCING METHOXYIMINO ACETIC AMIDE | BAYER CROPSCIENCE AG (DE) | 2004-11-03 | — | — | EP | disclosed |
| EP-0846691-B1 | Process for preparation of 3-(1-hydroxyphenyl-1-alkoximinomethyl)dioxazines | BAYER CROPSCIENCE AG (DE) | 2004-06-30 | — | — | EP | disclosed |
| US-6730799-B2 | O-HYDROXYETHYL-O'-METHYL-BENZOFURANDIONE DIOXIMES ARE REARRANGED IN THE PRESENCE OF A DILUENT AND IN THE PRESENCE OF AN ACID OR A BASE | BAYER AKTIENGESELLSCHAFT (DE) | 2004-05-04 | — | — | US | disclosed |
| US-6660872-B1 | In high yields | BAYER AKTIENGESELLSCHAFT (DE) | 2003-12-09 | — | — | US | disclosed |
| EP-1188753-B1 | Intermediates in the preparation of 3-(1-hydroxyphenyl-1-alkoximinomethyl)dioxazines | BAYER CROPSCIENCE AG (DE) | 2003-09-24 | — | — | EP | disclosed |
| EP-0904268-B1 | PROCESSES FOR PREPARING 3-(1-HYDROXYPHENYL-1-ALKOXIMINOMETHYL)DIOXAZINES | BAYER CROPSCIENCE AG (DE) | 2002-12-04 | — | — | EP | disclosed |
| US-20020169316-A1 | Process for preparing 3-(1-hydroxyphenyl-1-alkoximinomethyl) dioxazines | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-14 | — | — | US | disclosed |
| US-6479675-B1 | Processes for preparing 3-(1-hydroxyphenyl-1-alkoximinomethyl) dioxazines | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-12 | — | — | US | disclosed |
| US-6462205-B1 | E ISOMERS ARE FORMED PREDOMINANTLY IN HIGH YIELDS | BAYER AKTIENGESELLSCAHFT (DE) | 2002-10-08 | — | — | US | disclosed |
| US-6437153-B1 | O-HYDROXYETHYL-O'-ALKYLBENZOFURANDIONE DIOXIMES REARRANGED IN THE PRESENCE OF A DILENT, AN ACID OR A BASE; FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-20 | — | — | US | disclosed |
| EP-1021431-A1 | METHOD FOR PREPARING OPTIONALLY SUBSTITUTED BENZOFURANONES | BAYER AG (DE) | 2000-07-26 | — | — | EP | disclosed |
| US-6093837-A | INTERMEDIATES FOR PREPARING COMPOUNDS HAVING FUNGICIDAL PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-25 | — | — | US | disclosed |
| EP-1003742-A1 | METHOXIMINOMETHYLOXADIAZINES USED AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2000-05-31 | — | — | EP | disclosed |
| US-6005104-A | INTERMEDIATES FOR PREPARING COMPOUNDS HAVING FUNGICIDAL PROPERTIES; PREPARED BY REARRANGING O-HYDROXYETHYL-O'-ALKYL-BENZOFURANDIONE DIOXIMES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |
| WO-1999057116-A2 | PESTICIDAL METHOXIMINOMETHYLOXATHIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-11 | — | — | WO | disclosed |
| WO-1999019316-A1 | METHOD FOR PREPARING OPTIONALLY SUBSTITUTED BENZOFURANONES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-04-22 | — | — | WO | disclosed |
| EP-0904268-A1 | PROCESSES FOR PREPARING 3-(1-HYDROXYPHENYL-1-ALKOXIMINOMETHYL)DIOXAZINES | BAYER AG (DE) | 1999-03-31 | — | — | EP | disclosed |
| WO-1999009026-A1 | METHOXIMINOMETHYLOXADIAZINES USED AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-25 | — | — | WO | disclosed |
| EP-0846691-A1 | Process for preparation of 3-(1-hydroxyphenyl-1-alkoximinomethyl)dioxazines | BAYER AG (DE) | 1998-06-10 | — | — | EP | disclosed |
| WO-1997046542-A1 | PROCESSES FOR PREPARING 3-(1-HYDROXYPHENYL-1-ALKOXIMINOMETHYL)DIOXAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020169316-A1 | Process for preparing 3-(1-hydroxyphenyl-1-alkoximinomethyl) dioxazines | CYP4Z1, CYP4X1, CYP51A1 | MEN1 3281/4885KMT2A 2368/4885STK17B 1491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.