SCHEMBL6655441

SCHEMBL6655441

CC1OC1Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 1/20 0.43
TP53 P04637 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
SLC6A3 Q01959 1/20 0.40
CTRB1 P17538 1/20 0.40
NOS1 P29475 2/20 0.39
NOS2 P35228 2/20 0.39
FASN P49327 1/20 0.39
GBA1 P04062 1/20 0.38
CALM1 P0DP23 1/20 0.38
EP300 Q09472 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2947513 1.00 TLR9 (0.43) TLR9TP53SLC6A2SLC6A4SLC6A3
SCHEMBL31231840 0.82 TLR9 (0.47) TLR9TP53SLC6A2SLC6A4SLC6A3
SCHEMBL6297171 0.80 HTR6 (0.49)
SCHEMBL9132394 0.79 TP53 (0.39) TLR9TP53
SCHEMBL873745 0.79 SLC6A2 (0.39) TP53SLC6A2SLC6A4SLC6A3NOS1
SCHEMBL9132875 0.79 IDO1 (0.41)
SCHEMBL9132910 0.78 KDM4E (0.46)
SCHEMBL31595612 0.77 TP53 (0.42) TLR9TP53SLC6A2SLC6A4SLC6A3
SCHEMBL9133277 0.77 IDO1 (0.39) SLC6A2SLC6A4SLC6A3
SCHEMBL14087418 0.77 IDO1 (0.39) SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120058644-A Synthesis method of (S) -oxetane-2-methylamine and intermediate thereof 苏州华先医药科技有限公司 2025-05-30 CN disclosed
CN-119948373-A Optical film 大仓工业株式会社 2025-05-06 CN disclosed
CN-112745779-A Fluororesin substrate laminate 昭和电工材料株式会社 2021-05-04 CN disclosed
CN-101781268-B Isothiazolone substituted benzene dicarboxylic acid derivatives and their use for preparing beta-secretase inhibitors INST PHARM & TOXICOLOGY AMMS 2012-05-30 CN disclosed
CN-1898248-B Process for the preparation of (3r,3as,6ar)-hexahydrofuro [2,3-b] furan-3-yl (1s,2r)-3-[[(4-aminophenyl) sulfonyl] (isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate TIBOTEC PHARM LTD 2011-08-17 CN disclosed
CN-101781268-A Isothiazole ketone substituted benzene dicarboxylic acid derivative and usage thereof in preparation of beta-secretase inhibitor INST PHARM & TOXICOLOGY AMMS 2010-07-21 CN disclosed
CN-1898248-A Process for the preparation of (3r,3as,6ar)-hexahydrofuro [2,3-b] furan-3-yl (1s,2r)-3-[[(4-aminophenyl) sulfonyl] (isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate TIBOTEC PHARM LTD (IE) 2007-01-17 CN disclosed
EP-1428818-A2 Method for producing N-carbamate-protected beta-aminoepoxide and beta-aminoalcohol Ajinomoto Co., Inc. (JP) 2004-06-16 EP disclosed
US-5466838-A Catalytic reaction of olefin with oxygen in the presence of aldehyde SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-11-14 US disclosed
EP-0540009-B1 Process for producing epoxides SUMITOMO CHEMICAL CO (JP) 1995-08-30 EP disclosed
US-5367087-A Process for producing epoxide SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-22 US disclosed
EP-0540009-A1 Process for producing epoxides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-05-05 EP disclosed
EP-0064165-B1 ANTIHYPERTENSIVE AGENTS PENNWALT CORPORATION (US) 1987-06-10 EP disclosed
US-4186255-A POLYURETHANE CATALYST TEXACO DEVELOPMENT CORPORATION (US) 1980-01-29 US disclosed
US-4136240-A METALLIC QUATERNARY AMMONIUM CARBOXYLATES AS POLYISOCYANURATE CATALYSTS TEXACO DEVELOPMENT CORPORATION (US) 1979-01-23 US disclosed