Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.75 |
| ▸ | CA2 | P00918 | 6/20 | 0.75 |
| ▸ | CA9 | Q16790 | 5/20 | 0.75 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3068132 | 1.00 | CA12 (0.75) | CA12CA2CA9SIRT2MAPT | |
| Hydrochloric Acid SCHEMBL30532247 | 0.96 | CA12 (0.70) | CA12CA2CA9SIRT2MAPT | |
| SCHEMBL803089 | 0.86 | CA12 (1.00) | CA12CA2CA9SIRT2MAPT | |
| SCHEMBL29359256 | 0.86 | CA12 (1.00) | CA12CA2CA9SIRT2MAPT | |
| SCHEMBL710477 | 0.86 | CA12 (1.00) | CA12CA2CA9SIRT2MAPT | |
| SCHEMBL710476 | 0.86 | CA12 (1.00) | CA12CA2CA9SIRT2MAPT | |
| SCHEMBL30361105 | 0.86 | CA12 (1.00) | CA12CA2CA9SIRT2MAPT | |
| SCHEMBL25379604 | 0.84 | CA12 (0.96) | CA12CA2CA9SIRT2MAPT | |
| SCHEMBL31540902 | 0.84 | CA12 (0.96) | CA12CA2CA9SIRT2MAPT | |
| SCHEMBL348136 | 0.84 | CA12 (0.88) | CA12CA2CA9SIRT2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017167638-A1 | NON-AQUEOUS ELECTROLYTES AND USES THEREOF | SONY CORPORATION (JP) | 2017-10-05 | — | — | WO | disclosed |
| US-20110172234-A1 | METHODS AND COMPOSITIONS OF TRAIL-DEATH RECEPTOR AGONISTS/ACTIVATORS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2011-07-14 | — | — | US | disclosed |
| US-20110172234-A1 | METHODS AND COMPOSITIONS OF TRAIL-DEATH RECEPTOR AGONISTS/ACTIVATORS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2011-07-14 | — | — | US | disclosed |
| US-7915245-B2 | Using small molecules as binding ligands, for the recruitment of Fas-associated death domain protein, activation of death-inducing signaling complex, caspase-8, and apoptosis in malignant cells; anticarcinogens, antitumor agents; enhanced cellular differentiation, minimizing cytolysis to healthy cells | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2011-03-29 | — | — | US | disclosed |
| US-7915245-B2 | Using small molecules as binding ligands, for the recruitment of Fas-associated death domain protein, activation of death-inducing signaling complex, caspase-8, and apoptosis in malignant cells; anticarcinogens, antitumor agents; enhanced cellular differentiation, minimizing cytolysis to healthy cells | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2011-03-29 | — | — | US | disclosed |
| CN-101709097-A | Olefin polymerization catalyst for coordinating [O-N-S] type tridentate ligand with titanium metal and preparation method thereof | UNIV FUDAN | 2010-05-19 | — | — | CN | disclosed |
| US-20100044088-A1 | CONDUCTIVE ADHESIVE | ABLESTIK (JAPAN) CO. LTD. (JP) | 2010-02-25 | — | — | US | disclosed |
| US-20100044088-A1 | CONDUCTIVE ADHESIVE | ABLESTIK (JAPAN) CO. LTD. (JP) | 2010-02-25 | — | — | US | disclosed |
| EP-2042580-A1 | CONDUCTIVE ADHESIVE | Ablestik (Japan) Co., Ltd. (JP) | 2009-04-01 | — | — | EP | disclosed |
| US-20080214547-A1 | METHODS AND COMPOSITIONS OF TRAIL-DEATH RECEPTOR AGONISTS/ACTIVATORS | UNIVERSITY OF MARYLAND, BALTIMORE | 2008-09-04 | — | — | US | disclosed |
| US-20080214547-A1 | METHODS AND COMPOSITIONS OF TRAIL-DEATH RECEPTOR AGONISTS/ACTIVATORS | UNIVERSITY OF MARYLAND, BALTIMORE | 2008-09-04 | — | — | US | disclosed |
| EP-1423467-A1 | FLUXING COMPOSITIONS | 3M Innovative Properties Company (US) | 2004-06-02 | — | — | EP | disclosed |
| US-20030111519-A1 | Fluxing compositions | 3M INNOVATIVE PROPERTIES COMPANY | 2003-06-19 | — | — | US | disclosed |
| WO-2003020816-A1 | FLUXING COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-03-13 | — | — | WO | disclosed |
| US-5426085-A | Used in pressure sensitive carbonless copoly-papers; image formed by reaction of color forming compound and transition metal compound | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-06-20 | — | — | US | disclosed |
| US-5376451-A | Aromatic substituted compounds capable of forming coordination compounds with transition metal salts; used in pressure sensitive carbonless copy-papers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-12-27 | — | — | US | disclosed |
| WO-1992000199-A1 | YELLOW COLOR-FORMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214547-A1 | METHODS AND COMPOSITIONS OF TRAIL-DEATH RECEPTOR AGONISTS/ACTIVATORS | BID, BAD, MCL1 | CA12 1940/4885CA2 2958/4885CA9 2391/4885 |
| US-20110172234-A1 | METHODS AND COMPOSITIONS OF TRAIL-DEATH RECEPTOR AGONISTS/ACTIVATORS | BID, BAD, MCL1 | CA12 1940/4885CA2 2958/4885CA9 2391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.