Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.70 |
| ▸ | CA2 | P00918 | 5/20 | 0.70 |
| ▸ | CA9 | Q16790 | 4/20 | 0.70 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6655954 | 0.96 | CA12 (0.75) | CA12CA2CA9SIRT2MAPT | |
| SCHEMBL3068132 | 0.96 | CA12 (0.75) | CA12CA2CA9SIRT2MAPT | |
| SCHEMBL803089 | 0.83 | CA12 (1.00) | CA12CA2CA9SIRT2MAPT | |
| SCHEMBL29359256 | 0.83 | CA12 (1.00) | CA12CA2CA9SIRT2MAPT | |
| SCHEMBL30361105 | 0.83 | CA12 (1.00) | CA12CA2CA9SIRT2MAPT | |
| SCHEMBL710476 | 0.83 | CA12 (1.00) | CA12CA2CA9SIRT2MAPT | |
| SCHEMBL710477 | 0.83 | CA12 (1.00) | CA12CA2CA9SIRT2MAPT | |
| SCHEMBL25379604 | 0.81 | CA12 (0.96) | CA12CA2CA9SIRT2MAPT | |
| SCHEMBL3395482 | 0.81 | CA12 (0.96) | CA12CA2CA9SIRT2MAPT | |
| SCHEMBL4774107 | 0.81 | CA12 (0.96) | CA12CA2CA9SIRT2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116751325-B | Preparation method and system of polyolefin | 中国石油天然气股份有限公司 | 2025-06-24 | — | — | CN | disclosed |
| WO-2024250506-A1 | CONTINUOUS SOLUTION POLYMERIZATION METHOD AND SYSTEM | 中国石油天然气股份有限公司 | 2024-12-12 | — | — | WO | disclosed |
| CN-116655841-B | Continuous solution polymerization method and system | 中国石油天然气股份有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-116751325-A | Preparation method and system of polyolefin | 中国石油天然气股份有限公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-116655841-A | Continuous solution polymerization method and system | 中国石油天然气股份有限公司 | 2023-08-29 | — | — | CN | disclosed |