SCHEMBL6656490

SCHEMBL6656490

CCCCCC=CC(=O)Oc1ccc(-c2ccc(CCC)s2)cc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 5/20 0.40
CNR2 P34972 3/20 0.40
THRB P10828 2/20 0.40
ZDHHC2 Q9UIJ5 1/20 0.36
LTA4H P09960 3/20 0.36
PPARA Q07869 1/20 0.36
HTR1A P08908 3/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2E1 P05181 1/20 0.35
CYP3A4 P08684 1/20 0.35
ALOX5 P09917 1/20 0.35
CYP2C8 P10632 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2A6 P11509 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2B6 P20813 1/20 0.35
CYP2C19 P33261 1/20 0.35
TRPV1 Q8NER1 1/20 0.35
EPHX2 P34913 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6656484 1.00 CNR1 (0.40) CNR1CNR2THRBZDHHC2LTA4H
SCHEMBL6657883 0.96 THRB (0.38) CNR1CNR2THRBZDHHC2LTA4H
SCHEMBL6657880 0.96 THRB (0.38) CNR1CNR2THRBZDHHC2LTA4H
SCHEMBL6663210 0.95 THRB (0.42) CNR1CNR2THRBZDHHC2LTA4H
SCHEMBL6663205 0.95 THRB (0.42) CNR1CNR2THRBZDHHC2LTA4H
SCHEMBL6656923 0.93 THRB (0.42) CNR1CNR2THRBZDHHC2LTA4H
SCHEMBL6656918 0.93 THRB (0.42) CNR1CNR2THRBZDHHC2LTA4H
SCHEMBL6657454 0.92 THRB (0.39) THRBTRPV1
SCHEMBL6657449 0.92 THRB (0.39) THRBTRPV1
SCHEMBL6664189 0.91 THRB (0.42) CNR1CNR2THRBZDHHC2PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1165721-B1 LIQUID CRYSTALLINE ALKENYL COMPOUNDS INCORPORATING AN HETEROCYCLIC FIVE-MEMBERED RING QINETIQ LTD (GB) 2004-08-04 EP disclosed
US-6696110-B1 THERMOGRAPHY QINETIQ LIMITED (GB) 2004-02-24 US disclosed