SCHEMBL6656602

SCHEMBL6656602

C=C(C)C(=O)O[SiH]1CCCCO1.O=C(c1ccccc1)c1ccccc1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.41
LIG1 P18858 1/20 0.40
LMNA P02545 4/20 0.38
HPGD P15428 4/20 0.38
ALDH1A1 P00352 3/20 0.38
HTT P42858 3/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2C19 P33261 2/20 0.38
PGR P06401 1/20 0.38
CYP2D6 P10635 1/20 0.38
SLC6A2 P23975 1/20 0.38
PDE4A P27815 1/20 0.38
MAPK1 P28482 1/20 0.38
HRH1 P35367 1/20 0.38
SLC6A3 Q01959 1/20 0.38
PDE4D Q08499 1/20 0.38
STS P08842 1/20 0.37
PIK3CD O00329 1/20 0.36
PIK3CA P42336 1/20 0.36
PIK3CB P42338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL876640 0.76 ALDH1A1 (0.38) ALDH1A1TSHR
Methacrylic Acid SCHEMBL18986073 0.75 LIG1 (0.59) ELANELIG1LMNAHPGDALDH1A1
SCHEMBL30887182 0.71 ELANE (0.70) ELANELIG1LMNAHPGDALDH1A1
Methyl Alcohol SCHEMBL28795496 0.70 LIG1 (0.70) LIG1LMNAHPGDALDH1A1HTT
Formaldehyde SCHEMBL588098 0.70 LIG1 (0.70) LIG1LMNAHPGDALDH1A1HTT
Ethane SCHEMBL28106767 0.70 LIG1 (0.70) LIG1LMNAHPGDALDH1A1HTT
SCHEMBL36215 0.70 LIG1 (0.76) LIG1LMNAHPGDALDH1A1HTT
SCHEMBL29390505 0.70 LIG1 (0.76) LIG1LMNAHPGDALDH1A1HTT
SCHEMBL22129808 0.70 LIG1 (0.76) LIG1LMNAHPGDALDH1A1HTT
Benzene SCHEMBL6034371 0.70 LIG1 (0.76) LIG1LMNAHPGDALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1083844-B1 INTRAOCULAR LENS BENZ RES & DEV CORP (US) 2004-06-16 EP disclosed
US-6517750-B2 Polymerizing mixture comprising a hydrophilic monomer, an alkoxyalkyl methacrylate monomer, and crosslinking monomer to form copolymer; forming copolymer into one-piece intraocular lens BENZ RESEARCH AND DEVELOPMENT CORPORATION 2003-02-11 US disclosed
US-20020027302-A1 Intraocular lens BENZ RESEARCH AND DEVELOPMENT CORPORATION 2002-03-07 US disclosed
US-6267784-B1 FOLDABLE SO AS TO BE INSERTABLE THROUGH A SMALL INCISION IN THE EYE BENZ RESEARCH AND DEVELOPMENT CORPORATION 2001-07-31 US disclosed
EP-1083844-A1 INTRAOCULAR LENS Benz Research and Development Corporation (US) 2001-03-21 EP disclosed
WO-1999056672-A1 INTRAOCULAR LENS BENZ RESEARCH AND DEVELOPMENT CORPORATION (US) 1999-11-11 WO disclosed