SCHEMBL665661

SCHEMBL665661

CCC(C)(C)c1ccc(OP(=O)(O)O)cc1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
BLM P54132 1/20 0.54
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
MAPT P10636 1/20 0.50
SRC P12931 1/20 0.47
POLB P06746 1/20 0.46
CYP2C9 P11712 1/20 0.46
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CYP2C19 P33261 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
INPPL1 O15357 2/20 0.42
INPP5A Q14642 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
HRH3 Q9Y5N1 5/20 0.41
MAOB P27338 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL665660 0.85 NPC1 (0.53) NPC1RAB9AMAPTPOLBCYP2C9
SCHEMBL1354466 0.84 CYP3A4 (0.54) BLMSRCCA1CA2SMN1; SMN2
SCHEMBL27470623 0.83 NPC1 (0.45) BLMNPC1RAB9AMAPTPOLB
SCHEMBL8660502 0.83 NPC1 (0.45) BLMNPC1RAB9AMAPTPOLB
SCHEMBL28964419 0.83 BLM (0.51) BLMSRCCA1CA2CYP2C19
SCHEMBL5679042 0.82 BLM (0.47) BLMSRC
SCHEMBL11307783 0.82 NPC1 (0.50) NPC1RAB9AMAPTPOLBCYP2C9
SCHEMBL1815086 0.81 SRC (0.54) BLMMAPTSRCCA1CA2
SCHEMBL284462 0.81 SRC (0.54) BLMNPC1RAB9AMAPTSRC
SCHEMBL27876498 0.80 SRC (0.47) BLMNPC1RAB9ASRCPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2885825-B1 SALTS OF PHOSPHORUS OXIDE AS N-DOPANTS FOR ORGANIC ELECTRONICS SIEMENS AG (DE) 2016-07-06 EP claimed
US-20150255719-A1 SALTS OF PHOSPHORUS OXIDE AS N-DOPANTS FOR ORGANIC ELECTRONICS SIEMENS AKTIENGESELLSCHAFT (DE) 2015-09-10 US claimed
CN-102942775-A Polycarbonate with reduced color SABIC INNOVATIVE PLASTICS IP 2013-02-27 CN claimed
CN-101484530-B Polycarbonate with reduced color SABIC INNOVATIVE PLASTICS IP 2013-01-02 CN claimed
US-7645851-B2 Polycarbonate with reduced color SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-01-12 US claimed
CN-101484530-A Polycarbonate with reduced color SABIC INNOVATIVE PLASTICS IP (NL) 2009-07-15 CN claimed
EP-2035500-A2 POLYCARBONATE WITH REDUCED COLOR Sabic Innovative Plastics IP B.V. (NL) 2009-03-18 EP claimed
WO-2008005655-A2 POLYCARBONATE WITH REDUCED COLOR SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-01-10 WO claimed
US-20080004379-A1 Polycarbonate with Reduced Color GENERAL ELECTRIC COMPANY (US) 2008-01-03 US claimed
EP-0532753-B1 COMPOSITE METALLIC POWDER COMPOSITION AND PRODUCTION THEREOF ASAHI CHEMICAL METALS (JP) 1997-01-15 EP claimed
US-20210338610-A1 AMINO-ARYL-BENZAMIDE COMPOUNDS AND METHODS OF USE THEREOF HEPANOVA, INC. 2021-11-04 US disclosed
US-11000491-B2 Amino-aryl-benzamide compounds and methods of use thereof HEPANOVA, INC. (US) 2021-05-11 US disclosed
CN-104662687-B Salts of phosphorus oxide for use as n-type dopants in organic electronic devices 西门子公司 2019-06-14 CN disclosed
US-9806266-B2 Salts of phosphorus oxide as N-dopants for organic electronics SIEMENS AKTIENGESELLSCHAFT (DE) 2017-10-31 US disclosed
CN-105189604-A Production of a polycarbonate with limited metal residuals SABIC INNOVATIVE PLASTICS IP 2015-12-23 CN disclosed
EP-2035500-A2 POLYCARBONATE WITH REDUCED COLOR Sabic Innovative Plastics IP B.V. (NL) 2009-03-18 EP disclosed
WO-2008005633-A1 METHOD FOR MAKING MOLDED POLYCARBONATE ARTICLES WITH IMPROVED COLOR SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-01-10 WO disclosed
WO-2008005655-A2 POLYCARBONATE WITH REDUCED COLOR SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-01-10 WO disclosed
US-20080004379-A1 Polycarbonate with Reduced Color GENERAL ELECTRIC COMPANY (US) 2008-01-03 US disclosed
US-20080004407-A1 Molding polycarbonate resin made by a transesterification reaction using an activated diaryl carbonate such that the polycarbonate is susceptible to formation of internal ester linkages (IEL), and controlling (IEL) through incorporation of phosphite additive that inhibits the linkages GENERAL ELECTRIC COMPANY (US) 2008-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11000491-B2 Amino-aryl-benzamide compounds and methods of use thereof AADAC, GOT2, ABAT BLM 2191/4885NPC1 166/4885RAB9A 2856/4885
US-20210338610-A1 AMINO-ARYL-BENZAMIDE COMPOUNDS AND METHODS OF USE THEREOF AADAC, GOT2, ABAT BLM 2191/4885NPC1 166/4885RAB9A 2856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.