Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 1/20 | 0.33 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2337867 | 0.90 | PLK1 (0.36) | LATS1LATS2CA12CA1CA2 | |
| SCHEMBL8626480 | 0.84 | CA12 (0.36) | LATS1LATS2CA12CA1CA2 | |
| SCHEMBL6620058 | 0.84 | CXCR2 (0.31) | LATS1LATS2CA12CA1CA2 | |
| SCHEMBL2341320 | 0.82 | CA12 (0.34) | CA12CA1CA2CA9CA14 | |
| SCHEMBL4264934 | 0.80 | LATS1 (0.40) | LATS1LATS2CA12CA1CA2 | |
| SCHEMBL6619437 | 0.79 | CXCR2 (0.35) | LATS1LATS2CA12CA1CA2 | |
| SCHEMBL6618235 | 0.78 | KDM4C (0.44) | LATS1LATS2CA12CA1CA2 | |
| SCHEMBL6618264 | 0.78 | KDM4C (0.44) | LATS1LATS2CA12CA1CA2 | |
| SCHEMBL6618236 | 0.78 | KDM4C (0.44) | LATS1LATS2CA12CA1CA2 | |
| SCHEMBL6617764 | 0.77 | HCAR3 (0.38) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877748-B1 | PYRIDO-1,2,4-THIADIAZINE AND PYRIDO-1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | UNIV LIEGE (BE) | 2004-11-03 | — | — | EP | disclosed |
| US-5792764-A | ENDOCRINE DISORDERS ESPECIALLY AS A K(ATP)-CHANNEL MODULATOR | NOVO NORDISK A/S (DK) | 1998-08-11 | — | — | US | disclosed |