Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6656949 | 1.00 | THRB (0.39) | THRBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6659640 | 0.99 | THRB (0.40) | THRBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6659633 | 0.99 | THRB (0.40) | THRBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6665305 | 0.92 | THRB (0.42) | THRBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6665298 | 0.92 | THRB (0.42) | THRBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6660632 | 0.91 | THRB (0.38) | THRBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6660629 | 0.91 | THRB (0.38) | THRBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6664777 | 0.90 | THRB (0.43) | THRBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6664773 | 0.90 | THRB (0.43) | THRBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6657454 | 0.90 | THRB (0.39) | THRBHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165721-B1 | LIQUID CRYSTALLINE ALKENYL COMPOUNDS INCORPORATING AN HETEROCYCLIC FIVE-MEMBERED RING | QINETIQ LTD (GB) | 2004-08-04 | — | — | EP | disclosed |
| US-6696110-B1 | THERMOGRAPHY | QINETIQ LIMITED (GB) | 2004-02-24 | — | — | US | disclosed |