Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 10/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6658616 | 0.92 | MEN1 (0.51) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL6656984 | 0.91 | MEN1 (0.51) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL6662210 | 0.90 | MAPT (0.56) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL6659831 | 0.89 | MEN1 (0.51) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL6656820 | 0.89 | DRD2 (0.54) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL6659094 | 0.87 | MAOB (0.54) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL6660189 | 0.87 | DRD2 (0.46) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL6662627 | 0.85 | MEN1 (0.41) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL6661644 | 0.85 | DRD2 (0.50) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6658613 | 0.84 | PPARG (0.46) | MEN1KMT2AL3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | disclosed |