Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6652751 | 0.86 | TLR8 (0.58) | TLR8KMT2AL3MBTL1ACHEKDM4E | |
| SCHEMBL7978785 | 0.84 | TLR8 (0.52) | TLR8PTGER4KMT2AL3MBTL1ACHE | |
| SCHEMBL6653088 | 0.83 | TLR8 (0.68) | TLR8KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL6080442 | 0.77 | MAPK1 (0.51) | TLR8PTGER4KMT2AKDM4EALDH1A1 | |
| SCHEMBL6654439 | 0.76 | TLR8 (0.46) | TLR8KMT2AACHEKDM4EALDH1A1 | |
| SCHEMBL12397237 | 0.74 | HTT (0.62) | KMT2AL3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL9375371 | 0.72 | CCR1 (0.48) | L3MBTL1KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL22090002 | 0.71 | KMT2A (0.42) | KMT2AL3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL16487216 | 0.70 | TLR8 (1.00) | TLR8ALDH1A1HTTPOLB | |
| SCHEMBL7975692 | 0.70 | TLR8 (0.49) | TLR8KMT2AACHEKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | disclosed |