SCHEMBL6657737

SCHEMBL6657737

c1ccc(-c2ccccc2/N=N/c2cccc(-c3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 1/20 0.57
SENP8 Q96LD8 1/20 0.57
SENP7 Q9BQF6 1/20 0.57
SENP6 Q9GZR1 1/20 0.57
SIGMAR1 Q99720 2/20 0.39
HNF4A P41235 1/20 0.37
ALDH1A1 P00352 4/20 0.37
HSD17B10 Q99714 2/20 0.37
HPGD P15428 1/20 0.37
BCL2L1 Q07817 1/20 0.37
CYP2A6 P11509 1/20 0.37
MAPK1 P28482 1/20 0.37
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
LMNA P02545 2/20 0.34
MAPT P10636 2/20 0.34
HTT P42858 2/20 0.34
NPC1 O15118 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3266658 0.88 CASP3 (0.63) CASP3SENP8SENP7SENP6HNF4A
SCHEMBL3999159 0.87 CASP3 (0.71) CASP3SENP8SENP7SENP6SIGMAR1
SCHEMBL3266654 0.87 CASP3 (0.71) CASP3SENP8SENP7SENP6SIGMAR1
Methane SCHEMBL3133791 0.84 CASP3 (0.68) CASP3SENP8SENP7SENP6SIGMAR1
SCHEMBL5008914 0.83 CASP3 (0.42) CASP3SENP8SENP7SENP6SIGMAR1
SCHEMBL5012498 0.83 CASP3 (0.41) CASP3SENP8SENP7SENP6SIGMAR1
SCHEMBL9017632 0.82 CASP3 (0.55) CASP3SENP8SENP7SENP6SIGMAR1
SCHEMBL29499160 0.80 CASP3 (0.83) CASP3SENP8SENP7SENP6SIGMAR1
SCHEMBL6540764 0.79 CASP3 (0.38) CASP3SENP8SENP7SENP6SIGMAR1
SCHEMBL10408854 0.78 CASP3 (0.50) CASP3SENP8SENP7SENP6HNF4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0456659-B1 CHARGE DIRECTOR COMPOSITION HEWLETT PACKARD INDIGO BV (NL) 2004-06-30 EP disclosed
EP-0472627-B1 HUMIDITY TOLERANT CHARGE DIRECTOR COMPOSITIONS INDIGO NV (NL) 1996-01-10 EP disclosed
US-5286593-A Liquid developer containing stabilized charge director composition SPECTRUM SCIENCES B.V. (NL) 1994-02-15 US disclosed
US-5264313-A Lecithin is stqbilized by polyvinylpyrrolidone polymer; useful for forming electronstatic images SPECTRUM SCIENCES B.V. (NL) 1993-11-23 US disclosed
EP-0472627-A1 HUMIDITY TOLERANT CHARGE DIRECTOR COMPOSITIONS. SPECTRUM SCIENCES BV (NL) 1992-03-04 EP disclosed
EP-0456659-A1 CHARGE DIRECTOR COMPOSITION INDIGO N.V. (NL) 1991-11-21 EP disclosed
US-5047306-A Humidity tolerant charge director compositions SPECTRUM SCIENCES B. V. (NL) 1991-09-10 US disclosed
WO-1990014617-A1 HUMIDITY TOLERANT CHARGE DIRECTOR COMPOSITIONS SPECTRUM SCIENCES B.V. (NL) 1990-11-29 WO disclosed
WO-1990008983-A1 CHARGE DIRECTOR COMPOSITION SAVIN CORPORATION (US) 1990-08-09 WO disclosed
US-4401742-A POLYMERIZATION, WITH ESTERIFICATION OF AN ALCOHOLIC DISPERSANT PITNEY BOWES INC. (US) 1983-08-30 US disclosed