Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | RAD52 | P43351 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6657753 | 1.00 | MAPT (0.45) | MAPTMEN1KMT2APOLBMAPK1 | |
| Trifluoroacetic Acid SCHEMBL6660230 | 1.00 | MAPT (0.45) | MAPTMEN1KMT2APOLBMAPK1 | |
| Trifluoroacetic Acid SCHEMBL6660175 | 0.95 | MAPT (0.49) | MAPTMEN1KMT2APOLBMAPK1 | |
| Trifluoroacetic Acid SCHEMBL6662414 | 0.95 | MAPT (0.49) | MAPTMEN1KMT2APOLBMAPK1 | |
| Trifluoroacetic Acid SCHEMBL6665222 | 0.94 | MAPT (0.42) | MAPTMEN1KMT2APOLBMAPK1 | |
| Trifluoroacetic Acid SCHEMBL6659461 | 0.94 | MAPT (0.42) | MAPTMEN1KMT2APOLBMAPK1 | |
| Trifluoroacetic Acid SCHEMBL6664129 | 0.93 | MAPT (0.47) | MAPTMEN1KMT2APOLBMAPK1 | |
| Trifluoroacetic Acid SCHEMBL6663851 | 0.93 | MAPT (0.47) | MAPTMEN1KMT2APOLBMAPK1 | |
| Trifluoroacetic Acid SCHEMBL6660806 | 0.92 | MAPT (0.47) | MAPTMEN1KMT2APOLBMAPK1 | |
| Trifluoroacetic Acid SCHEMBL6662447 | 0.92 | MAPT (0.47) | MAPTMEN1KMT2APOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087935-B1 | ANTHRACENE DERIVATIVES AS ANTI-CANCER AGENTS | BTG INT LTD (GB) | 2004-08-18 | — | — | EP | disclosed |
| US-20030203975-A1 | Anti-cancer agents | BTG INTERNATIONAL LIMITED (GB) | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203975-A1 | Anti-cancer agents | TOP2B, TOP2A, TOP1 | MAPT 4879/4885MEN1 3787/4885KMT2A 3724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.