Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1D | O15297 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27547776 | 1.00 | PPM1D (0.32) | PPM1D | |
| SCHEMBL6651067 | 1.00 | PPM1D (0.32) | PPM1D | |
| SCHEMBL1797519 | 0.94 | PPM1D (0.34) | PPM1D | |
| SCHEMBL6652402 | 0.88 | CHRM2 (0.33) | PPM1D | |
| SCHEMBL7525409 | 0.88 | CHRM2 (0.33) | PPM1D | |
| SCHEMBL6653252 | 0.86 | CHRM2 (0.34) | PPM1D | |
| SCHEMBL15301704 | 0.86 | CHRM2 (0.34) | PPM1D | |
| SCHEMBL15301702 | 0.86 | CHRM2 (0.34) | PPM1D | |
| SCHEMBL19336162 | 0.86 | CHRM2 (0.34) | PPM1D | |
| SCHEMBL4606860 | 0.86 | CHRM2 (0.34) | PPM1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1094060-B1 | New process for the preparation of retiferol derivatives | BASILEA PHARMACEUTICA AG (CH) | 2004-04-28 | — | — | EP | disclosed |
| US-6437142-B1 | 10,10,10-TRIFLUORO-5,5-DIMETHYL-9-TRIETHYLSILANYLOXY-9-TRIFLUO ROMETHYL-DEC-7-ENAL REACTED WITH TRIETHYL PHOSPHONOACETATE OR ETHYL (TRIMETHYLSILYL) ACETATE AND THEN COUPLING WITH 2-MERCAPTO-BENZOTHIAZOLE | BASILEA PHARMACEUTICA AG (CH) | 2002-08-20 | — | — | US | disclosed |
| US-6403346-B1 | FOR TREATMENT/PREVENTION OF HYPERPROLIFERATIVE SKIN DISEASES (PSORIASIS) AND REVERSING CONDITIONS ASSOCIATED WITH PHOTODAMAGE | BASILEA PHARMACEUTICA AG (CH) | 2002-06-11 | — | — | US | disclosed |
| US-20020028975-A1 | Process for preparing retiferol derivatives | HILPERT HANS (CH) | 2002-03-07 | — | — | US | disclosed |
| US-6310262-B1 | COUPLING CYCLOHEXANONE DERIVATIVE WITH BENZOTHIAZOLE DERIVATIVE TO FORM RETIFEROL DERIVATIVE | BASILEA PHARMACEUTICA AG (CH) | 2001-10-30 | — | — | US | disclosed |
| CN-1293179-A | New method of preparing Latif alcohol derivative | HOFFMANN LA ROCHE (CH) | 2001-05-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028975-A1 | Process for preparing retiferol derivatives | RBP1, RBP4, NR1H2 | PPM1D 1999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.