SCHEMBL6657971

SCHEMBL6657971

CCC(=O)c1ccc(O)c(C(C)(C)Cn2nc3ccccc3n2)c1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALPL P05186 5/20 0.40
ALPG P10696 5/20 0.40
PLAA Q9Y263 2/20 0.40
ALPP P05187 1/20 0.40
HSP90AA1 P07900 11/20 0.40
HSP90AB1 P08238 8/20 0.40
TDP1 Q9NUW8 1/20 0.40
MAPT P10636 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
HTT P42858 1/20 0.38
F2R P25116 1/20 0.38
HSP90B1 P14625 1/20 0.38
ALPI P09923 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL135249 0.76 FFAR1 (0.40)
SCHEMBL27857309 0.74 HSP90AA1 (0.47) HSP90AA1HSP90AB1MAPTSMN1; SMN2L3MBTL1
SCHEMBL11605049 0.74 NPC1 (0.57) ALPLALPGPLAAALPPTDP1
SCHEMBL13078326 0.74 HSP90AA1 (0.64) HSP90AA1HSP90AB1MAPTSMN1; SMN2L3MBTL1
SCHEMBL27452478 0.70 ALDH1A1 (0.49) HSP90AA1HSP90AB1MAPTSMN1; SMN2L3MBTL1
SCHEMBL19138732 0.69 F2R (0.48) F2R
SCHEMBL3761349 0.68 HSP90AA1 (0.38) HSP90AA1HSP90AB1TDP1MAPTALDH1A1
SCHEMBL10630720 0.66 NPC1 (0.43) HSP90AA1HSP90AB1TDP1MAPTSMN1; SMN2
SCHEMBL2991009 0.65 CA12 (0.58) ALPLALPGPLAAMAPTL3MBTL1
SCHEMBL30389755 0.65 CA12 (0.58) ALPLALPGPLAAMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040167255-A1 Stabilizer composition EVERLIGHT USA, INC. 2004-08-26 US claimed
EP-1439206-A2 Stabilizer composition Everlight USA, Inc. (US) 2004-07-21 EP claimed