Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.60 |
| ▸ | AKT1 | P31749 | 1/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31214345 | 0.88 | DYRK1A (0.72) | DYRK1AAKT1PIK3CAMTORNPC1 | |
| SCHEMBL1671036 | 0.84 | NPC1 (0.54) | DYRK1AAKT1PIK3CAMTORNPC1 | |
| SCHEMBL18042122 | 0.84 | DYRK1A (0.48) | DYRK1AAKT1PIK3CAMTORNPC1 | |
| SCHEMBL6032917 | 0.83 | DYRK1A (0.62) | DYRK1APIK3CANPC1RAB9AAPP | |
| Ammonia Solution, Strong SCHEMBL28327531 | 0.82 | NPC1 (0.53) | DYRK1AAKT1PIK3CAMTORNPC1 | |
| SCHEMBL24155396 | 0.81 | DYRK1A (0.60) | DYRK1AAKT1PIK3CAMTORNPC1 | |
| SCHEMBL16573976 | 0.81 | DYRK1A (0.60) | DYRK1ANPC1RAB9AAPPVRK1 | |
| SCHEMBL22130152 | 0.81 | DYRK1A (0.70) | DYRK1APIK3CANPC1RAB9AAPP | |
| SCHEMBL27558183 | 0.81 | DYRK1A (0.60) | DYRK1ANPC1RAB9AAPPVRK1 | |
| Hydrazine SCHEMBL27557475 | 0.81 | NPC1 (0.51) | DYRK1AAKT1PIK3CAMTORNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004010761-A2 | PESTICIDAL CYANINE DYE DERIVATIVES | FMC CORPORATION (US) | 2004-02-05 | — | — | WO | disclosed |