SCHEMBL31214345

SCHEMBL31214345

c1nc2ccc(-c3ccc4ncsc4c3)cc2s1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.72
KDM4E B2RXH2 1/20 0.55
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
HKDC1 Q2TB90 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
ALDH1A1 P00352 1/20 0.54
HSD17B10 Q99714 1/20 0.54
APP P05067 1/20 0.53
RIPK1 Q13546 1/20 0.53
VRK1 Q99986 1/20 0.50
FFAR1 O14842 1/20 0.48
MAPK14 Q16539 1/20 0.48
TGFBR1 P36897 9/20 0.47
BMPR1A P36894 1/20 0.47
SMAD2 Q15796 1/20 0.47
AKT1 P31749 1/20 0.44
PIK3CA P42336 1/20 0.44
MTOR P42345 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6032917 0.90 DYRK1A (0.62) DYRK1AKDM4ENPC1RAB9AHKDC1
SCHEMBL22130152 0.88 DYRK1A (0.70) DYRK1AKDM4ENPC1RAB9AHKDC1
SCHEMBL16573976 0.88 DYRK1A (0.60) DYRK1AKDM4ENPC1RAB9AHKDC1
SCHEMBL27558183 0.88 DYRK1A (0.60) DYRK1AKDM4ENPC1RAB9AHKDC1
SCHEMBL6658073 0.88 DYRK1A (0.60) DYRK1AKDM4ENPC1RAB9AHKDC1
SCHEMBL17691820 0.87 DYRK1A (0.63) DYRK1AKDM4ENPC1RAB9AHKDC1
SCHEMBL27550527 0.87 DYRK1A (0.63) DYRK1AKDM4ENPC1RAB9AHKDC1
SCHEMBL17231495 0.85 DYRK1A (0.57) DYRK1AKDM4ENPC1RAB9AHKDC1
SCHEMBL17231480 0.85 DYRK1A (0.57) DYRK1AKDM4ENPC1RAB9AHKDC1
SCHEMBL12614654 0.84 DYRK1A (0.55) DYRK1AKDM4ENPC1RAB9AHKDC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4695322-A2 CONJUGATE ACID PROTON EXCHANGE POLYMERS AND METHODS OF MAKING AND USING CONJUGATE ACID PROTON EXCHANGE POLYMERS 1S1 Energy, Inc. (US) 2026-02-18 EP disclosed
WO-2024211793-A2 CONJUGATE ACID PROTON EXCHANGE POLYMERS AND METHODS OF MAKING AND USING CONJUGATE ACID PROTON EXCHANGE POLYMERS 1S1 ENERGY, INC. (US) 2024-10-10 WO disclosed