SCHEMBL6658152

SCHEMBL6658152

CC1(C)C[Si](C)(C)[Si](C)(C)[Si](C)(CCCN)O1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27167203 0.84
SCHEMBL4941497 0.82
SCHEMBL29207806 0.74
SCHEMBL2522524 0.73
SCHEMBL2564225 0.71
SCHEMBL1696074 0.70
SCHEMBL4940551 0.70 HRH3 (0.31)
SCHEMBL21641950 0.63
SCHEMBL21641955 0.62
SCHEMBL9986444 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12116442-B2 Method for producing silicone hydrogel contact lenses ALCON INC. (CH) 2024-10-15 US claimed
EP-4146461-B1 METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-03-13 EP claimed
EP-4146461-A1 METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2023-03-15 EP claimed
WO-2021224855-A1 METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2021-11-11 WO claimed
US-20210347929-A1 METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2021-11-11 US claimed
EP-1136514-B1 Poly (Aminoorganofunctionalsiloxanes) CLARIANT LSM ITALIA SPA (US) 2004-08-04 EP claimed
US-6339137-B1 MIXING 3-(3-AMINOPROPYL)HEPTAMETHYLTRISILOXANE BASIC CATALYST; HEATING THE MIXTURE TO PRODUCE POLY(3-AMINOPROPYLMETHYLSILOXANE)HOMOPOLYMER AND HEXAMETHYLDISILOXANE AND EVACUATING THE MIXTURE TO REMOVE ARCHIMICA (FLORIDA) INC. 2002-01-15 US claimed
EP-1136514-A2 Poly (Aminoorganofunctionalsiloxanes) Clariant Life Science Molecules (Florida) Inc. (US) 2001-09-26 EP claimed
US-5892084-A Aminoorganofunctionalsiloxanes PCR, INC. (US) 1999-04-06 US claimed
US-12116442-B2 Method for producing silicone hydrogel contact lenses ALCON INC. (CH) 2024-10-15 US disclosed
CN-118043331-A Preparation of amino-functional organosilicon compounds 陶氏环球技术有限责任公司 2024-05-14 CN disclosed
CN-118019747-A Preparation of propylimine-functionalized organosilicon compounds and primary aminopropyl-functionalized organosilicon compounds 陶氏环球技术有限责任公司 2024-05-10 CN disclosed
CN-118019748-A Preparation of imine-and primary amino-functional organosilicon compounds 陶氏环球技术有限责任公司 2024-05-10 CN disclosed
EP-4146461-B1 METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-03-13 EP disclosed
US-6339137-B1 MIXING 3-(3-AMINOPROPYL)HEPTAMETHYLTRISILOXANE BASIC CATALYST; HEATING THE MIXTURE TO PRODUCE POLY(3-AMINOPROPYLMETHYLSILOXANE)HOMOPOLYMER AND HEXAMETHYLDISILOXANE AND EVACUATING THE MIXTURE TO REMOVE ARCHIMICA (FLORIDA) INC. 2002-01-15 US disclosed
EP-1136514-A2 Poly (Aminoorganofunctionalsiloxanes) Clariant Life Science Molecules (Florida) Inc. (US) 2001-09-26 EP disclosed
EP-1068213-A4 NOVEL AMINOORGANOFUNCTIONALSILOXANES ARCHIMICA FLORIDA INC (US) 2001-05-02 EP disclosed
EP-1068213-A1 NOVEL AMINOORGANOFUNCTIONALSILOXANES ARCHIMICA (FLORIDA), Inc. (US) 2001-01-17 EP disclosed
WO-1999038872-A1 NOVEL AMINOORGANOFUNCTIONALSILOXANES ARCHIMICA (FLORIDA) INC. (US) 1999-08-05 WO disclosed
US-5892084-A Aminoorganofunctionalsiloxanes PCR, INC. (US) 1999-04-06 US disclosed