Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2410543 | 0.95 | HTT (0.37) | TSHRHTTHSD17B10CYP3A4USP2 | |
| SCHEMBL10766116 | 0.91 | TSHR (0.36) | TSHRHTTHSD17B10CYP3A4USP2 | |
| SCHEMBL7745536 | 0.88 | HTT (0.40) | TSHRHTTHSD17B10CYP3A4USP2 | |
| SCHEMBL4424301 | 0.88 | TSHR (0.48) | TSHRHTTCYP3A4MEN1THRB | |
| SCHEMBL4433315 | 0.86 | TSHR (0.46) | TSHRHTTCYP3A4USP2MEN1 | |
| SCHEMBL1274298 | 0.86 | HTT (0.39) | TSHRHTTHSD17B10CYP3A4USP2 | |
| SCHEMBL6659201 | 0.84 | HTT (0.42) | TSHRHTTHSD17B10CYP3A4USP2 | |
| SCHEMBL5178951 | 0.84 | HTT (0.42) | TSHRHTTHSD17B10CYP3A4USP2 | |
| SCHEMBL17262664 | 0.84 | HTT (0.42) | TSHRHTTHSD17B10CYP3A4USP2 | |
| SCHEMBL1342489 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004003050-A1 | POLYETHER URETHANE AMINES | HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) | 2004-01-08 | — | — | WO | disclosed |
| EP-1366102-A1 | HYDROXYL-GROUP-CONTAINING POLYETHER AMINE ADDUCTS | Vantico GmbH & Co. KG (DE) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002044240-A1 | HYDROXYL-GROUP-CONTAINING POLYETHER AMINE ADDUCTS | VANTICO GMBH & CO. KG (DE) | 2002-06-06 | — | — | WO | disclosed |
| WO-1999037714-A1 | PROPOXYLATED PHENOLS AND/OR PROPOXYLATED AROMATIC ALCOHOLS AS PLASTICISERS FOR EPOXY RESINS AND AMINIC EPOXY RESIN HARDENERS | CIBA SPEZIALITÄTENCHEMIE BERGKAMEN GMBH (DE) | 1999-07-29 | — | — | WO | disclosed |