SCHEMBL665844

SCHEMBL665844

[C]1=CCOS1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL431362 0.65
SCHEMBL5318324 0.52
SCHEMBL1190870 0.39
SCHEMBL23964 0.39
SCHEMBL2554291 0.36
SCHEMBL248228 0.36
SCHEMBL4175824 0.36
SCHEMBL16553398 0.26
SCHEMBL4093276 0.26
Hydrogen Sulfide SCHEMBL15941638 0.26

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118234720-A Radiolabeled fibroblast activation protein ligand 菲罗化学股份公司 2024-06-21 CN disclosed
EP-3715350-B1 ARYLPHOSPHINE OXIDES FOR INHIBITING KINASE ACTIVITY SHENZHEN TARGETRX INC (CN) 2024-05-08 EP disclosed
US-11958870-B2 Spiro-containing platinum(II) emitters with tunable emission energies and syntheses thereof THE UNIVERSITY OF HONG KONG (CN) 2024-04-16 US disclosed
EP-3715343-B1 DIPHENYLAMINOPYRIMIDINE COMPOUND FOR INHIBITING KINASE ACTIVITY SHENZHEN TARGETRX INC (CN) 2024-02-14 EP disclosed
CN-111132974-B Sulfonamide carboxamide compounds 英夫拉索姆有限公司 2023-11-21 CN disclosed
CN-116917278-A Divalent fibroblast activation protein ligands for targeted delivery applications 菲罗化学股份公司 2023-10-20 CN disclosed
EP-3492462-B1 AMINO PYRIMIDINE COMPOUND FOR INHIBITING PROTEIN TYROSINE KINASE ACTIVITY SHENZHEN TARGETRX INC (CN) 2023-08-30 EP disclosed
CN-116635037-A Mountain lotus leaf apigenin analogue as antiviral agent 香港浸会大学 2023-08-22 CN disclosed
US-20220389038-A1 ANTIVIRAL NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR SHENZHEN TARGETRX, INC. (CN) 2022-12-08 US disclosed
US-11389463-B2 Antiviral nucleoside reverse transcriptase inhibitor SHENZHEN TARGETRX, INC. (CN) 2022-07-19 US disclosed
US-20120046291-A1 Extended Triterpene Derivatives MYREXIS, INC. 2012-02-23 US disclosed
US-20090311403-A1 Method of Using Organic Compounds GIVAUDAN SA (CH) 2009-12-17 US disclosed
EP-2046147-A1 METHOD OF USING ORGANIC COMPOUNDS Givaudan SA (CH) 2009-04-15 EP disclosed
EP-1828223-A4 NOVEL BETULIN DERIVATIVES, PREPARATION THEREOF AND USE THEREOF PANACOS PHARMACEUTICALS INC (US) 2009-03-11 EP disclosed
WO-2008011742-A1 METHOD OF USING ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2008-01-31 WO disclosed
EP-1828223-A2 NOVEL BETULIN DERIVATIVES, PREPARATION THEREOF AND USE THEREOF Panacos Pharmaceuticals, Inc. (US) 2007-09-05 EP disclosed
US-20060205697-A1 Novel betulin derivatives, preparation thereof and use thereof MYREXIS, INC. 2006-09-14 US disclosed
WO-2006053255-A2 NOVEL BETULIN DERIVATIVES, PREPARATION THEREOF AND USE THEREOF PANACOS PHARMACEUTICALS, INC. (US) 2006-05-18 WO disclosed
US-5059608-A Anticonvulsants, antiischemic agents FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1991-10-22 US disclosed
EP-0336228-A1 Tetrahydroisoquinolines and tetrahydrobenzazepines and a process for the preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-10-11 EP disclosed