Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 18/20 | 0.80 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.80 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.80 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.80 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.80 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14906447 | 1.00 | ADORA1 (0.80) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| SCHEMBL6660602 | 0.94 | ADORA3 (0.86) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| SCHEMBL6660596 | 0.94 | ADORA3 (0.86) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| SCHEMBL13454893 | 0.90 | ADORA1 (0.84) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| SCHEMBL14903071 | 0.90 | ADORA1 (0.84) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| SCHEMBL13075647 | 0.89 | ADORA1 (0.77) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| Tecadenoson SCHEMBL24838611 | 0.89 | ADORA1 (1.00) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| Tecadenoson SCHEMBL6226634 | 0.89 | ADORA1 (1.00) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| Tecadenoson SCHEMBL22349437 | 0.89 | ADORA1 (1.00) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 | |
| Tecadenoson SCHEMBL472549 | 0.89 | ADORA1 (1.00) | ADORA1ADORA3ADORA2AADORA2BSLC28A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030856-B1 | ADENOSINE A1 RECEPTOR AGONISTS | GLAXO GROUP LTD (GB) | 2004-08-18 | — | — | EP | claimed |
| US-6740644-B2 | ADENOSINE DERIVATIVES, AGONISTS AT THE ADENOSINE A1 RECEPTOR | SMITHKLINE BEECHAM CORPORATION | 2004-05-25 | — | — | US | claimed |
| US-20030158146-A1 | Chemical compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2003-08-21 | — | — | US | claimed |
| EP-1030856-B1 | ADENOSINE A1 RECEPTOR AGONISTS | GLAXO GROUP LTD (GB) | 2004-08-18 | — | — | EP | disclosed |
| US-6740644-B2 | ADENOSINE DERIVATIVES, AGONISTS AT THE ADENOSINE A1 RECEPTOR | SMITHKLINE BEECHAM CORPORATION | 2004-05-25 | — | — | US | disclosed |
| US-20030158146-A1 | Chemical compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2003-08-21 | — | — | US | disclosed |
| US-6544960-B1 | Chemical compounds | SMITHKLINE BEECHAM CORPORATION | 2003-04-08 | — | — | US | disclosed |
| EP-1030856-A2 | ADENOSINE A1 RECEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999024451-A2 | ADENOSINE A1 RECEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 1999-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158146-A1 | Chemical compounds | CNR1, ADORA3, ADORA1 | ADORA1 3/4885ADORA3 2/4885ADORA2A 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.