Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL595004 | 0.87 | LMNA (0.46) | TDP1PDE4ALMNAL3MBTL1KDM4E | |
| SCHEMBL8679740 | 0.87 | LMNA (0.40) | TDP1PDE4ALMNAL3MBTL1KDM4E | |
| SCHEMBL11585200 | 0.85 | LMNA (0.44) | TDP1PDE4ALMNAL3MBTL1KDM4E | |
| SCHEMBL2026947 | 0.81 | TP53 (0.35) | ALDH1A1TP53MEN1KMT2ATSHR | |
| SCHEMBL3516865 | 0.81 | LMNA (0.39) | ALDH1A1TDP1PDE4ALMNAL3MBTL1 | |
| SCHEMBL13737428 | 0.79 | TDP1 (0.42) | ALDH1A1TDP1LMNATP53PRKCA | |
| SCHEMBL320232 | 0.79 | LMNA (0.48) | ALDH1A1TDP1LMNATP53KDM4E | |
| SCHEMBL30531662 | 0.79 | LMNA (0.48) | ALDH1A1TDP1LMNATP53KDM4E | |
| SCHEMBL31683702 | 0.79 | LMNA (0.48) | ALDH1A1TDP1LMNATP53KDM4E | |
| SCHEMBL537034 | 0.79 | TDP1 (0.35) | TDP1LMNATP53PRKCAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1440046-A1 | HYDROGENOLYSIS OF 6-CARBON SUGARS AND OTHER ORGANIC COMPOUNDS | BATTELLE MEMORIAL INSTITUTE (US) | 2004-07-28 | — | — | EP | disclosed |
| WO-2003035582-A1 | HYDROGENOLYSIS OF 6-CARBON SUGARS AND OTHER ORGANIC COMPOUNDS | BATTELLE MEMORIAL INSTITUTE (US) | 2003-05-01 | — | — | WO | disclosed |