Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | IDO1 | P14902 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2673969 | 0.86 | LOXL2 (0.59) | LOXL2ALDH1A1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11771000 | 0.85 | IDO1 (0.57) | LOXL2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5160372 | 0.82 | CYP2C19 (0.67) | LOXL2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6932662 | 0.82 | CYP2C19 (0.61) | LOXL2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL12953925 | 0.81 | LOXL2 (0.57) | LOXL2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1829314 | 0.81 | LOXL2 (0.57) | LOXL2ALDH1A1MAPTMEN1KMT2A | |
| Water SCHEMBL8902538 | 0.81 | CYP2C19 (0.65) | LOXL2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3344816 | 0.81 | CYP2C19 (0.56) | LOXL2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL12415768 | 0.81 | IDO1 (0.64) | LOXL2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL12415809 | 0.81 | IDO1 (0.64) | LOXL2ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403506-B | Preparation method of indole-2-carboxylic acid derivative | 江西亚太科技发展有限公司 | 2024-02-13 | — | — | CN | disclosed |
| WO-2004012506-A2 | ANTIMICROBIAL COMPOUNDS | EXEGENICS, INC. (US) | 2004-02-12 | — | — | WO | disclosed |