Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 7/20 | 0.54 |
| ▸ | THRB | P10828 | 7/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6657368 | 0.88 | THRA (0.56) | THRATHRBEPHX1EPHX2 | |
| SCHEMBL6661763 | 0.88 | THRA (0.54) | THRATHRBEPHX1EPHX2 | |
| SCHEMBL7062138 | 0.86 | THRA (0.55) | THRATHRBEPHX1EPHX2MAPT | |
| SCHEMBL6660362 | 0.85 | THRA (0.58) | THRATHRBEPHX1EPHX2 | |
| SCHEMBL6664792 | 0.84 | THRA (0.56) | THRATHRBEPHX1EPHX2 | |
| SCHEMBL6658204 | 0.82 | THRA (0.59) | THRATHRBMAPT | |
| SCHEMBL6659428 | 0.82 | THRA (0.58) | THRATHRBEPHX1EPHX2 | |
| SCHEMBL6656513 | 0.82 | THRA (0.58) | THRATHRBEPHX1EPHX2 | |
| SCHEMBL6656506 | 0.82 | THRA (0.58) | THRATHRBEPHX1EPHX2 | |
| SCHEMBL6660558 | 0.80 | THRA (0.56) | THRATHRBEPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157001-B1 | OXAMIC ACIDS AND DERIVATIVES AS THYROID RECEPTOR LIGANDS | PFIZER PROD INC (US) | 2004-08-04 | — | — | EP | claimed |