Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18759166 | 0.96 | ESR1 (0.31) | ESR1ESR2CYP3A4TDP1 | |
| SCHEMBL3943019 | 0.89 | PCSK9 (0.35) | ESR1ESR2CYP3A4TDP1 | |
| SCHEMBL163845 | 0.87 | TDP1 (0.41) | ESR1ESR2CYP3A4TDP1TP53 | |
| SCHEMBL372344 | 0.87 | PCSK9 (0.34) | TDP1TP53 | |
| SCHEMBL5921753 | 0.85 | TDP1 (0.39) | ESR1ESR2CYP3A4TDP1TP53 | |
| SCHEMBL3068169 | 0.85 | TDP1 (0.39) | ESR1ESR2CYP3A4TDP1TP53 | |
| SCHEMBL9650051 | 0.85 | TDP1 (0.39) | ESR1ESR2CYP3A4TDP1TP53 | |
| SCHEMBL3997009 | 0.85 | TDP1 (0.39) | ESR1ESR2CYP3A4TDP1TP53 | |
| Hydrochloric Acid SCHEMBL6250361 | 0.85 | TDP1 (0.39) | ESR1ESR2CYP3A4TDP1TP53 | |
| Hydrochloric Acid SCHEMBL7505836 | 0.85 | TDP1 (0.39) | ESR1ESR2CYP3A4TDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030120006-A1 | In mold addition polymerization of norbornene-type monomers using group 10 metal complexes | THE B.F. GOODRICH COMPANY | 2003-06-26 | — | — | US | claimed |
| EP-1123916-B1 | Process for the preparation of amino diphenylamines | BAYER AG (DE) | 2004-08-04 | — | — | EP | disclosed |
| EP-1437340-A1 | Process for the preparation of aminodiphenylamines | Bayer Aktiengesellschaft (DE) | 2004-07-14 | — | — | EP | disclosed |
| EP-1081128-B1 | Process for the preparation of nitrodiphenylamines | BAYER AG (DE) | 2003-04-16 | — | — | EP | disclosed |
| EP-1123916-A1 | Process for the preparation of amino diphenylamines | BAYER AG (DE) | 2001-08-16 | — | — | EP | disclosed |
| US-6235937-B1 | Process for the preparation of nitrodiphenylamines | BAYER AKTIENGESELLSCHAFT (DE) | 2001-05-22 | — | — | US | disclosed |
| EP-1081128-A1 | Process for the preparation of nitrodiphenylamines | Bayer Aktiengesellschaft (DE) | 2001-03-07 | — | — | EP | disclosed |
| EP-0343954-B1 | Aromatic steroid 5-alpha-reductase inhibitors | SMITHKLINE BEECHAM CORP (US) | 1994-11-30 | — | — | EP | disclosed |
| WO-1989011282-A1 | AROMATIC STEROID 5-alpha-REDUCTASE INHIBITORS | SMITHKLINE BECKMAN CORPORATION (US) | 1989-11-30 | — | — | WO | disclosed |