Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6662257 | 0.89 | TSHR (0.50) | TSHRTHRBHCAR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL23149231 | 0.84 | TSHR (0.35) | TSHRTHRBCASP1 | |
| SCHEMBL5861520 | 0.83 | TSHR (0.42) | TSHRTHRBHCAR2CASP1ALDH1A1 | |
| SCHEMBL6658380 | 0.83 | CASP1 (0.46) | TSHRTHRBCASP1ALDH1A1GAA | |
| SCHEMBL4653225 | 0.82 | TSHR (0.41) | TSHRTHRBHCAR2CASP1ALDH1A1 | |
| SCHEMBL28005423 | 0.81 | TSHR (0.38) | TSHRTHRB | |
| SCHEMBL28779027 | 0.80 | CYP2D6 (0.42) | TSHRALDH1A1SMN1; SMN2LMNACHRM1 | |
| SCHEMBL6657047 | 0.80 | TSHR (0.40) | TSHRTHRBHCAR2CASP1ALDH1A1 | |
| SCHEMBL2818114 | 0.80 | TSHR (0.40) | TSHRTHRBHCAR2CASP1ALDH1A1 | |
| SCHEMBL1593009 | 0.79 | TSHR (0.42) | TSHRTHRBHCAR2CASP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123915-B1 | Process for producing alpha, beta-unsaturated carboxylic acid esters and catalyst for use in such process | NIPPON CATALYTIC CHEM IND (JP) | 2004-07-28 | — | — | EP | disclosed |
| US-6541656-B2 | Reacting an alpha, beta unsaturated carboxylic acid ester with a heterocyclic oxygen nitrogen, or sulfur compound | NIPPON SHOKUBAI COMPANY, LTD. (JP) | 2003-04-01 | — | — | US | disclosed |
| US-20010034300-A1 | Reacting an alpha, beta unsaturated carboxylic acid ester with a heterocyclic oxygen nitrogen, or sulfur compound | NIPPON SHOKUBAI COMPANY LTD. (JP) | 2001-10-25 | — | — | US | disclosed |
| EP-1123915-A1 | Process for producing alpha, beta-unsaturated carboxylic acid esters and catalyst for use in such process | Nippon Shokubai Co., Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |