Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 8/20 | 0.44 |
| ▸ | SSTR1 | P30872 | 6/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677243 | 0.84 | MRGPRX4 (0.42) | ARSSTR4HPGDRXRARXRB | |
| SCHEMBL6655948 | 0.84 | NPC1 (0.45) | ARSSTR4SSTR1PPARGPPARD | |
| SCHEMBL21748887 | 0.80 | SSTR4 (0.55) | SSTR4SSTR1PPARGPPARDPPARA | |
| SCHEMBL5511674 | 0.79 | AR (0.46) | ARSSTR4SSTR1HPGDTP53 | |
| SCHEMBL21748810 | 0.74 | SSTR4 (0.53) | SSTR4SSTR1PPARGPPARDPPARA | |
| SCHEMBL19139302 | 0.73 | MCHR1 (0.47) | ARSSTR4SSTR1HPGDTP53 | |
| SCHEMBL11032100 | 0.73 | HPGD (0.48) | SSTR4SSTR1PPARGPPARDPPARA | |
| SCHEMBL21749119 | 0.73 | SSTR4 (0.61) | SSTR4SSTR1HPGDTP53RXRA | |
| SCHEMBL10064784 | 0.72 | L3MBTL1 (0.49) | SSTR4SSTR1HPGDTP53RXRA | |
| SCHEMBL18391357 | 0.70 | SSTR4 (0.45) | ARSSTR4SSTR1HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242913-A1 | Organic compounds | DUCRAY PIERRE (FR) | 2004-12-02 | — | — | US | disclosed |
| EP-1436250-A1 | CYANOACETYL COMPOUNDS | Novartis AG (CH) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003031394-A1 | ORGANIC COMPOUNDS | NOVARTIG AG (CH) | 2003-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242913-A1 | Organic compounds | CYP1B1, BCL2A1, CYP1A1 | AR 6/4885SSTR4 3431/4885SSTR1 2155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.