Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.42 |
| ▸ | MEN1 | O00255 | 13/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.42 |
| ▸ | HTT | P42858 | 12/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 8/20 | 0.37 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | THRB | P10828 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14274879 | 0.79 | MAPT (0.66) | MAPTMEN1KMT2AHTTKDM4E | |
| SCHEMBL16523149 | 0.79 | MAPT (0.66) | MAPTMEN1KMT2AHTTKDM4E | |
| SCHEMBL10189054 | 0.72 | HTT (0.67) | MAPTMEN1KMT2AHTTKDM4E | |
| SCHEMBL5551010 | 0.72 | HTT (0.67) | MAPTMEN1KMT2AHTTKDM4E | |
| SCHEMBL11870832 | 0.71 | MAPT (0.43) | MAPTMEN1KMT2AHTTKDM4E | |
| SCHEMBL17472378 | 0.70 | MEN1 (0.43) | MAPTMEN1KMT2AHTTKDM4E | |
| SCHEMBL16520749 | 0.69 | CASP1 (0.46) | MAPTMEN1KMT2AHTTKDM4E | |
| SCHEMBL5464267 | 0.68 | HTT (0.67) | MAPTMEN1KMT2AHTTKDM4E | |
| SCHEMBL5464265 | 0.68 | HTT (0.67) | MAPTMEN1KMT2AHTTKDM4E | |
| SCHEMBL16423541 | 0.67 | TSHR (0.34) | MAPTMEN1KMT2AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1287086-B1 | HYBRID POLYMER MATERIAL FOR PHOTOCHROMIC COATINGS AND OPTICAL ARTICLES AND GLAZINGS COATED THEREWITH | FRAUNHOFER GES FORSCHUNG (DE) | 2004-08-18 | — | — | EP | disclosed |
| EP-1287086-A1 | HYBRID POLYMER MATERIAL FOR PHOTOCHROMIC COATINGS AND OPTICAL ARTICLES AND GLAZINGS COATED THEREWITH | FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001090268-A1 | HYBRID POLYMER MATERIAL FOR PHOTOCHROMIC COATINGS AND OPTICAL ARTICLES AND GLAZINGS COATED THEREWITH | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2001-11-29 | — | — | WO | disclosed |
| EP-1110966-A2 | Silyl-carbamate photochromatic compounds process for their preparation and their use in polymeric materials | Great Lakes Chemical (Europe) GmbH (CH) | 2001-06-27 | — | — | EP | disclosed |