SCHEMBL6660735

SCHEMBL6660735

[CH2]CCCCCCCC[CH]CCCCCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.52
THRB P10828 1/20 0.42
FAAH O00519 2/20 0.41
TRPV1 Q8NER1 1/20 0.41
DNM1 Q05193 3/20 0.39
ALDH1A1 P00352 1/20 0.38
EP300 Q09472 1/20 0.37
MEN1 O00255 1/20 0.36
CYP3A4 P08684 1/20 0.36
KMT2A Q03164 1/20 0.36
GMNN O75496 1/20 0.35
USP2 O75604 1/20 0.35
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
ALOX15 P16050 1/20 0.35
APEX1 P27695 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7097960 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL9788915 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL2945293 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL9801443 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL9801390 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL9801641 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL9801103 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL235185 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL9801479 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL929008 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1244423-B1 ANTIPERSPIRANT COMPOSITION THAT CONTAINS A WATER-SOLUBLE ANTIPERSPIRANT ACTIVE AGENT HENKEL KGAA (DE) 2004-08-04 EP disclosed
EP-0691327-B1 AMINE DERIVATIVE AND DERMATOLOGIC PREPARATION CONTAINING THE SAME KAO CORP (JP) 1999-07-21 EP disclosed
US-5723497-A AMINE ALCOHOL DERIVATIVES FOR WRINKLE RESISTNCE KAO CORPORATION (JP) 1998-03-03 US disclosed
EP-0691327-A1 AMINE DERIVATIVE AND DERMATOLOGIC PREPARATION CONTAINING THE SAME Kao Corporation (JP) 1996-01-10 EP disclosed
US-4992150-A Telomer with alpha-olefin;oil and fuel additive NIPPON OIL CO, LTD. (JP) 1991-02-12 US disclosed
US-4943646-A WITH N-ORGANOHYDROXAMIC ACID MONSANTO COMPANY (US) 1990-07-24 US disclosed
US-4939299-A Succinyl dihydroxamic acids MONSANTO COMPANY (US) 1990-07-03 US disclosed
EP-0271468-A2 Gallium complexes and solvent extraction of gallium Monsanto Company (US) 1988-06-15 EP disclosed
US-4741887-A Gallium complexes and solvent extraction of gallium MONSANTO COMPANY (US) 1988-05-03 US disclosed
EP-0069067-B1 TRANSPARENT POLYAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE MANUFACTURE OF MOULDINGS CIBA-GEIGY AG (CH) 1985-03-20 EP disclosed
US-4429110-A HYDROLYTICALLY STABLE MOLDING MATERIALS CIBA-GEIGY CORPORATION (US) 1984-01-31 US disclosed