Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788915 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL2945293 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL9801443 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL9801390 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL6660735 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL9801641 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL9801103 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL235185 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL9801479 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL929008 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536445-A | Surfactant and dispersible or emulsifiable compositions employing surfactant | ZENECA LIMTED (GB) | 1996-07-16 | — | — | US | claimed |
| US-5300255-A | For preparing dispersions, emulsions; inks, paints | IMPERIAL CHEMICAL INDUSTRIES, PLC. (GB) | 1994-04-05 | — | — | US | claimed |
| CN-107365418-B | Polyallylamine derivatives | 味之素株式会社 | 2022-04-01 | — | — | CN | disclosed |
| US-10280267-B2 | Polyallylamine derivative | AJINOMOTO CO., INC. (JP) | 2019-05-07 | — | — | US | disclosed |
| US-20170327651-A1 | POLYALLYLAMINE DERIVATIVE | AJINOMOTO CO., INC. (JP) | 2017-11-16 | — | — | US | disclosed |
| US-20030009005-A1 | Acetoacetylated diamines and polyamines | LONZA AG (CH) | 2003-01-09 | — | — | US | disclosed |
| EP-1259479-A1 | ACETOACETYLATED DIAMINES AND POLYAMINES | Lonza AG (CH) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001064626-A1 | ACETOACETYLATED DIAMINES AND POLYAMINES | LONZA AG (CH) | 2001-09-07 | — | — | WO | disclosed |
| US-5801258-A | Amide derivatives and dermatologic preparations containing the same | KAO CORPORATION (JP) | 1998-09-01 | — | — | US | disclosed |
| US-5753707-A | TREATING SKIN DISORDER, DERMATITIS, ROUGH SKIN; BARRIER FUNCTION | KAO CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| EP-0623124-B1 | AMIDE DERIVATIVES AND DERMATOLOGIC PREPARATIONS CONTAINING THE SAME | KAO CORP (JP) | 1998-02-18 | — | — | EP | disclosed |
| US-5659052-A | APPLYING TO SKIN TO IMPROVE BARRIER FUNCTIONS OF HORNY LAYER | KAO CORPORATION (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0761644-A2 | Amide derivatives and their use in cosmetic composition | KAO CORPORATION (JP) | 1997-03-12 | — | — | EP | disclosed |
| WO-1994012490-A2 | AMIDE DERIVATIVES AND DERMATOLOGIC PREPARATIONS CONTAINING THE SAME | KAO CORPORATION (JP) | 1994-06-09 | — | — | WO | disclosed |
| US-5009986-A | Solubility in organic solvents, durability, compatibility with polymers | TEIJIN LIMITED (JP) | 1991-04-23 | — | — | US | disclosed |
| EP-0379277-A2 | Napthtalocyanine based compound and optical recording medium containing the same | TEIJIN LIMITED (JP) | 1990-07-25 | — | — | EP | disclosed |