Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2356674 | 0.91 | MEN1 (0.52) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| Trifluoroacetic Acid SCHEMBL7425553 | 0.86 | MEN1 (0.47) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| Trifluoroacetic Acid SCHEMBL7421431 | 0.86 | MEN1 (0.47) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| Trifluoroacetic Acid SCHEMBL6477387 | 0.85 | MEN1 (0.45) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL31694361 | 0.84 | MEN1 (0.49) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL20745043 | 0.84 | MEN1 (0.49) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL9588464 | 0.84 | MEN1 (0.49) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL16758734 | 0.84 | MEN1 (0.49) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL15352900 | 0.83 | MEN1 (0.47) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| Trifluoroacetic Acid SCHEMBL31732071 | 0.82 | MEN1 (0.44) | MEN1KMT2AALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082138-B1 | TEXAPHYRIN CONJUGATES AND USES THEREOF | UNIV TEXAS (US) | 2004-08-25 | — | — | EP | disclosed |
| US-6207660-B1 | Texaphyrin conjugates and uses thereof | PHARMACYCLICS, INC. | 2001-03-27 | — | — | US | disclosed |
| EP-1082138-A1 | TEXAPHYRIN CONJUGATES AND USES THEREOF | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999062551-A1 | TEXAPHYRIN CONJUGATES AND USES THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1999-12-09 | — | — | WO | disclosed |