Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6661048 | 0.85 | MEN1 (0.49) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| Trifluoroacetic Acid SCHEMBL1401787 | 0.84 | PKM (0.38) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL1401786 | 0.84 | PKM (0.38) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL7421431 | 0.83 | MEN1 (0.47) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| Trifluoroacetic Acid SCHEMBL7425553 | 0.83 | MEN1 (0.47) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| Trifluoroacetic Acid SCHEMBL6476259 | 0.83 | CXCR4 (0.43) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| Trifluoroacetic Acid SCHEMBL31732071 | 0.82 | MEN1 (0.44) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| Trifluoroacetic Acid SCHEMBL2356674 | 0.81 | MEN1 (0.52) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| Trifluoroacetic Acid SCHEMBL3470280 | 0.79 | ALOX15 (0.41) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL8438777 | 0.78 | CXCR4 (0.47) | MEN1KMT2AALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6962911-B2 | Pyrrolopyrimidinone derivatives, process of preparation and use | SK CHEMICALS CO., LTD. (KR) | 2005-11-08 | — | — | US | disclosed |
| EP-1257553-B1 | PYRROLOPYRIMIDINONE DERIVATIVES, PROCESS OF PREPARATION AND USE | SK CHEMICALS CO LTD (KR) | 2004-05-26 | — | — | EP | disclosed |
| EP-1257553-A1 | PYRROLOPYRIMIDINONE DERIVATIVES, PROCESS OF PREPARATION AND USE | SK Chemicals Co., Ltd. (KR) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001060825-A1 | PYRROLOPYRIMIDINONE DERIVATIVES, PROCESS OF PREPARATION AND USE | SK CHEMICALS CO., LTD. (KR) | 2001-08-23 | — | — | WO | disclosed |