Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6660926 | 0.91 | ALDH1A1 (0.55) | KDM4EALDH1A1GAASMN1; SMN2LMNA | |
| SCHEMBL6664267 | 0.85 | ACP3 (0.56) | ALDH1A1GAASMN1; SMN2LMNAKMT2A | |
| SCHEMBL6667125 | 0.85 | ALDH1A1 (0.48) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6665251 | 0.80 | ACP3 (0.55) | KDM4EALDH1A1GAASLC6A9SLC6A5 | |
| SCHEMBL6660475 | 0.74 | ALDH1A1 (0.44) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6662165 | 0.74 | ALDH1A1 (0.44) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6660044 | 0.72 | ALDH1A1 (0.42) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6660313 | 0.71 | GAA (0.45) | KDM4EALDH1A1GAASMN1; SMN2LMNA | |
| SCHEMBL6662450 | 0.71 | ACP3 (0.75) | ALDH1A1GAALMNAKMT2AMEN1 | |
| SCHEMBL9791412 | 0.70 | GAA (0.57) | KDM4EALDH1A1GAASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877028-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 1-AMINOPHOSPHONIC ACID DERIVATIVES AND NOVEL PHOSPHONATE COMPOUNDS | HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) | 1998-11-11 | — | — | EP | claimed |
| EP-0877028-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 1-AMINOPHOSPHONIC ACID DERIVATIVES AND NOVEL PHOSPHONATE COMPOUNDS | HOKKO CHEM IND CO (JP) | 2004-08-25 | — | — | EP | disclosed |
| US-6084123-A | REACTING AN IMINE WITH A PHOSPHONIC ACID ESTER USING AN ASYMMETRIC CATALYST OF A RARE EARTH METAL/ALKALI METAL-BINAPHTHOL COMPLEX; HYDROGENATION AND ACIDOLYSIS | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |
| EP-0877028-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 1-AMINOPHOSPHONIC ACID DERIVATIVES AND NOVEL PHOSPHONATE COMPOUNDS | HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |