Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.42 |
| ▸ | THRA | P10827 | 3/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6657178 | 1.00 | THRB (0.42) | THRBTHRAZDHHC2RARBMEN1 | |
| SCHEMBL6660673 | 1.00 | THRB (0.42) | THRBTHRAZDHHC2RARBMEN1 | |
| SCHEMBL6660682 | 1.00 | THRB (0.42) | THRBTHRAZDHHC2RARBMEN1 | |
| SCHEMBL6657175 | 1.00 | THRB (0.42) | THRBTHRAZDHHC2RARBMEN1 | |
| SCHEMBL6661076 | 1.00 | THRB (0.42) | THRBTHRAZDHHC2RARBMEN1 | |
| SCHEMBL6663350 | 0.99 | THRB (0.43) | THRBTHRAZDHHC2RARBMEN1 | |
| SCHEMBL6663341 | 0.99 | THRB (0.43) | THRBTHRAZDHHC2RARBMEN1 | |
| SCHEMBL6659031 | 0.98 | THRB (0.44) | THRBTHRAZDHHC2ALDH1A1MAPT | |
| SCHEMBL6659035 | 0.98 | THRB (0.44) | THRBTHRAZDHHC2ALDH1A1MAPT | |
| SCHEMBL6662330 | 0.95 | THRB (0.39) | THRBTHRAZDHHC2RARBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165721-B1 | LIQUID CRYSTALLINE ALKENYL COMPOUNDS INCORPORATING AN HETEROCYCLIC FIVE-MEMBERED RING | QINETIQ LTD (GB) | 2004-08-04 | — | — | EP | disclosed |
| US-6696110-B1 | THERMOGRAPHY | QINETIQ LIMITED (GB) | 2004-02-24 | — | — | US | disclosed |