SCHEMBL6661480

SCHEMBL6661480

CCC(C)(C)c1ccc(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.57
RAB9A P51151 4/20 0.57
LMNA P02545 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.40
MAPK1 P28482 1/20 0.40
CASP3 P42574 1/20 0.40
ATM Q13315 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40
KDM4E B2RXH2 2/20 0.39
POLB P06746 3/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
ESR1 P03372 5/20 0.36
ESR2 Q92731 3/20 0.36
AR P10275 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Octrizole SCHEMBL15508 0.87 NPC1 (0.56) NPC1RAB9ALMNASMN1; SMN2MAPK1
Octrizole SCHEMBL28983126 0.87 NPC1 (0.56) NPC1RAB9ALMNASMN1; SMN2MAPK1
Octrizole SCHEMBL29349945 0.87 NPC1 (0.56) NPC1RAB9ALMNASMN1; SMN2MAPK1
Octrizole SCHEMBL30315837 0.86 NPC1 (0.55) NPC1RAB9ALMNASMN1; SMN2MAPK1
SCHEMBL28357577 0.86 NPC1 (0.55) NPC1RAB9ALMNASMN1; SMN2KDM4E
SCHEMBL4954664 0.86 NPC1 (0.55) NPC1RAB9ALMNASMN1; SMN2KDM4E
SCHEMBL123853 0.85 NPC1 (0.51) NPC1RAB9ALMNACNR1CNR2
SCHEMBL28523920 0.85 NPC1 (0.42) NPC1RAB9ALMNASMN1; SMN2MAPK1
Octrizole SCHEMBL29281934 0.85 NPC1 (0.43) NPC1RAB9ALMNASMN1; SMN2MAPK1
SCHEMBL78159 0.85 NPC1 (0.64) NPC1RAB9ALMNASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677968-A Formula and preparation method of non-yellowing polyurethane sponge 伟建实业(苏州)有限公司 2023-02-03 CN claimed
EP-1238003-A1 MONO- AND BIS- BENZOTRIAZOLYLDIHYDROXYBIARYL UV ABSORBERS CYTEC TECHNOLOGY CORP. (US) 2002-09-11 EP claimed
WO-2001034694-A1 MONO- AND BIS- BENZOTRIAZOLYLDIHYDROXYBIARYL UV ABSORBERS CYTEC TECHNOLOGY CORP. (US) 2001-05-17 WO claimed
US-5624982-A BENZOTRIAZOLE COMPOUNDS FOR LIGHT STABILIZERS OF TETRAMETHYL PIPERIDINYL SEBACATE FOR STYRENE POLYMERS BAYER ANTWERPEN SA/NV (BE) 1997-04-29 US claimed
EP-0736064-A1 STABILIZER SYSTEM FOR NON YELLOWING POLYMER COMPOSITION BAYER ANTWERPEN N.V. (BE) 1996-10-09 EP claimed
US-5492948-A STABILIZER FOR STYRENE POLYMERS CONSISTING OF A BENZOTRIAZOLE, OLIGOMERIC CONDENSATE OF 2,4-DICHLORO-6-MORPHOLINO-S-TRIAZINE AND N,N*-/2,2,6,6-TETRAMETHYLPIPERIDYL/HEXAMETHYLENEDIAMINE, TRIS/3,5-DI-TERT-BUTYL-4-HYDROXYBENZYL/ ISOCYANURATE MONSANTO COMPANY (US) 1996-02-20 US claimed
WO-1995015358-A1 STABILIZER SYSTEM FOR NON YELLOWING POLYMER COMPOSITION BAYER ANTWERPEN SA/NV (BE) 1995-06-08 WO claimed
CN-113840872-B Phenol compound, resin composition, method for producing the same, and molded article 日本瑞翁株式会社 2023-04-18 CN disclosed
CN-115677968-A Formula and preparation method of non-yellowing polyurethane sponge 伟建实业(苏州)有限公司 2023-02-03 CN disclosed
CN-115003775-A Colorants for heat transfer fluids and compositions containing the same KD精细化工有限公司 2022-09-02 CN disclosed
CN-113840872-A Phenol compound, resin composition, process for producing the same, and molded article 日本瑞翁株式会社 2021-12-24 CN disclosed
CN-104114616-A Resin Additive Masterbatch ADEKA CORP 2014-10-22 CN disclosed
EP-0810086-B1 Sheet for illuminated signboard and illuminated signboard employing the same YUPO CORP (JP) 2004-09-01 EP disclosed
US-4973701-A LIGHT STABILIZERS FOR PHOTOGRAPHY AND POLYMERS CIBA-GEIGY CORPORATION (US) 1990-11-27 US disclosed
CN-1037337-A Substituted 2H-benzotriazole liquid mixtures CIBA GEIGY AG (CH) 1989-11-22 CN disclosed
US-4692400-A CONTAINING A UREIDO- AND ACYLAMINO-CONTAINING PHENOL-TYPE CYAN COUPLER AND NEGATIVE-TYPE CORESHELL SILVER HALIDE GRAINS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1987-09-08 US disclosed
EP-0201027-A2 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1986-11-12 EP disclosed
EP-0200206-A2 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1986-11-05 EP disclosed
EP-0199351-A2 Silver halide photographic material KONICA CORPORATION (JP) 1986-10-29 EP disclosed
US-4278589-A 2-[2-Hydroxy-3,5-di-(α,α-dimethylbenzyl)phenyl]-2H-benzotriazole and stabilized compositions CIBA-GEIGY CORPORATION (US) 1981-07-14 US disclosed