Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL480879 | 0.81 | KDM4E (0.31) | KDM4E | |
| SCHEMBL932028 | 0.67 | — | — | |
| SCHEMBL930057 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL933129 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL8468845 | 0.66 | — | — | |
| SCHEMBL10518267 | 0.64 | — | — | |
| SCHEMBL5153124 | 0.58 | — | — | |
| SCHEMBL8860545 | 0.58 | L3MBTL1 (0.77) | L3MBTL1KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL11598668 | 0.58 | L3MBTL1 (0.77) | L3MBTL1KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL1178666 | 0.58 | L3MBTL1 (0.40) | L3MBTL1KDM4EMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212327-B8 | PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS | ABBOTT GMBH & CO KG (DE) | 2004-02-25 | — | — | EP | disclosed |
| EP-1212327-A2 | PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001019829-A2 | PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-22 | — | — | WO | disclosed |