Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 9/20 | 0.66 |
| ▸ | CTSB | P07858 | 4/20 | 0.66 |
| ▸ | CTSS | P25774 | 1/20 | 0.66 |
| ▸ | CTSK | P43235 | 1/20 | 0.66 |
| ▸ | TACR1 | P25103 | 2/20 | 0.64 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13287011 | 0.95 | CTSL (0.62) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL8100468 | 0.95 | CTSL (0.62) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL8100557 | 0.92 | TACR1 (0.70) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL30241933 | 0.92 | TACR1 (0.70) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL7319412 | 0.92 | TACR1 (0.70) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL16095807 | 0.92 | TACR1 (0.70) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL12052836 | 0.92 | TACR1 (0.70) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL10049956 | 0.92 | TACR1 (0.70) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL30688477 | 0.92 | TACR1 (0.70) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL10722852 | 0.92 | TACR1 (0.70) | CTSLCTSBCTSSCTSKTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200457-B1 | CYSTEINE PROTEASE INHIBITORS | NAEJA PHARMACEUTICAL INC (CA) | 2004-08-25 | — | — | EP | disclosed |
| US-6635621-B1 | Alpha amino acid amide derivatives; reducing cathepsins B, L, S and/or K activity | NAEJA PHARMACEUTICAL INC. (CA) | 2003-10-21 | — | — | US | disclosed |
| EP-1200457-A2 | CYSTEINE PROTEASE INHIBITORS | Naeja Pharmaceutical Inc. (CA) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001009169-A2 | CYSTEINE PROTEASE INHIBITORS | NAEJA PHARMACEUTICAL INC (CA) | 2001-02-08 | — | — | WO | disclosed |