⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6661718 | 1.00 | — | — | |
| SCHEMBL6661703 | 1.00 | — | — | |
| SCHEMBL5831357 | 1.00 | — | — | |
| SCHEMBL6661721 | 1.00 | — | — | |
| SCHEMBL15723528 | 0.92 | — | — | |
| SCHEMBL6658884 | 0.92 | — | — | |
| SCHEMBL6658890 | 0.92 | — | — | |
| SCHEMBL6543457 | 0.92 | — | — | |
| SCHEMBL1271440 | 0.92 | — | — | |
| SCHEMBL11398745 | 0.90 | HSD11B1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118240233-A | Functionalized polymer grafted functionalized nano material composite modifier, modified asphalt and application thereof in coating waterproofing | 苏州非特兄弟新材料科技有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-117507540-A | Optical polyester film for flexible display | 合肥乐凯科技产业有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-117445523-A | Polyester film and preparation method thereof | 合肥乐凯科技产业有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-118240233-A | Functionalized polymer grafted functionalized nano material composite modifier, modified asphalt and application thereof in coating waterproofing | 苏州非特兄弟新材料科技有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-117507540-A | Optical polyester film for flexible display | 合肥乐凯科技产业有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-117445523-A | Polyester film and preparation method thereof | 合肥乐凯科技产业有限公司 | 2024-01-26 | — | — | CN | disclosed |
| EP-1012142-B1 | 2,3,5-TRISUBSTITUTED PYRIDINES AS INHIBITORS OF CYCLOOXYGENASE-2 | MERCK FROSST CANADA INC (CA) | 2004-08-11 | — | — | EP | disclosed |
| EP-1012142-A1 | 2,3,5-TRISUBSTITUTED PYRIDINES AS INHIBITORS OF CYCLOOXYGENASE-2 | Merck Frosst Canada & Co. (CA) | 2000-06-28 | — | — | EP | disclosed |
| US-6046217-A | TREATING AN INFLAMMATORY DISEASE SUSCEPTIBLE TO TREATMENT WITH A NON-STEROIDAL ANTI-INFLAMMATORY AGENT COMPRISING ADMINISTERING TO A PATIENT IN NEED OF SUCH TREATMENT A NONTOXIC 3-PHENYL SUBSTITUTED PYRIDINES | MERCK FROSST CANADA & CO. (CA) | 2000-04-04 | — | — | US | disclosed |
| WO-1999014194-A1 | 2,3,5-TRISUBSTITUTED PYRIDINES AS INHIBITORS OF CYCLOOXYGENASE-2 | MERCK FROSST CANADA & CO. (CA) | 1999-03-25 | — | — | WO | disclosed |