Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6661716 | 0.91 | DRD2 (0.39) | DRD2DRD3MCHR1DRD4HTR7 | |
| SCHEMBL6664810 | 0.83 | SLC6A4 (0.39) | SLC6A4DRD2DRD3MCHR1DRD4 | |
| SCHEMBL6660513 | 0.83 | SLC6A4 (0.37) | SLC6A4DRD2DRD3MCHR1DRD4 | |
| SCHEMBL5937197 | 0.83 | SLC6A4 (0.42) | SLC6A4DRD2CHRM1CHRM3 | |
| SCHEMBL6796355 | 0.82 | SLC6A4 (0.39) | SLC6A4DRD2 | |
| SCHEMBL5899925 | 0.79 | SLC6A4 (0.40) | SLC6A4DRD2CHRM3 | |
| Hydrochloric Acid SCHEMBL5899865 | 0.79 | SLC6A4 (0.39) | SLC6A4DRD2CHRM3 | |
| SCHEMBL5937192 | 0.78 | DRD2 (0.42) | DRD2DRD3MCHR1DRD4HTR7 | |
| SCHEMBL6708008 | 0.78 | SLC6A4 (0.40) | SLC6A4DRD2 | |
| SCHEMBL6790396 | 0.78 | DRD2 (0.39) | DRD2DRD3MCHR1DRD4HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004006923-A1 | ARYL PIPERIDINE DERIVATIVES AS INDUCERS OF LDL-RECEPTOR EXPRESSION FOR THE TREATMENT OF HYPERCHOLESTEROLEMIA | GLAXO GROUP LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |
| WO-2004006923-A1 | ARYL PIPERIDINE DERIVATIVES AS INDUCERS OF LDL-RECEPTOR EXPRESSION FOR THE TREATMENT OF HYPERCHOLESTEROLEMIA | GLAXO GROUP LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |