Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.44 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.44 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL333653 | 0.84 | SKP2 (0.61) | SKP2CYP3A4CYP2D6CYP2C9HPGD | |
| SCHEMBL3053597 | 0.83 | SKP2 (0.50) | SKP2CYP3A4CYP2D6CYP2C9HPGD | |
| SCHEMBL30883022 | 0.83 | SKP2 (0.50) | SKP2CYP3A4CYP2D6CYP2C9HPGD | |
| SCHEMBL5838115 | 0.81 | SKP2 (0.68) | SKP2CYP3A4CYP2D6CYP2C9HPGD | |
| SCHEMBL9193547 | 0.79 | TRPA1 (0.43) | HPGDNPC1MAPK1RAB9ACYP1A2 | |
| SCHEMBL10411345 | 0.78 | NPC1 (0.55) | SKP2CYP3A4HPGDNPC1MAPK1 | |
| SCHEMBL11467020 | 0.78 | SKP2 (0.65) | SKP2CYP3A4HPGDNPC1MAPK1 | |
| SCHEMBL11366320 | 0.78 | SKP2 (0.58) | SKP2CYP3A4CYP2D6CYP2C9HPGD | |
| SCHEMBL10938710 | 0.77 | SKP2 (0.53) | SKP2CYP3A4ALDH1A1HSD17B10KDM4E | |
| SCHEMBL8553254 | 0.77 | SKP2 (0.62) | SKP2CYP3A4HPGDNPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004009612-A1 | DEPROTECTION OF PHOSPHORUS IN OLIGONUCLEOTIDE SYNTHESIS | ISIS PHARMACEUTICALS, INC. (US) | 2004-01-29 | — | — | WO | disclosed |