SCHEMBL6662214

SCHEMBL6662214

CC1(C)CC(O[Si](OC2CC(C)(C)NC(C)(C)C2)(OC2CC(C)(C)NC(C)(C)C2)OC2CC(C)(C)NC(C)(C)C2)CC(C)(C)N1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.42
LMNA P02545 2/20 0.34
KDM4E B2RXH2 2/20 0.34
RECQL P46063 1/20 0.32
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
RAD52 P43351 1/20 0.32
GFER P55789 1/20 0.32
KMT2A Q03164 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KDM1A O60341 1/20 0.31
KCNH2 Q12809 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11151069 0.89 GAA (0.35) GAA
SCHEMBL314123 0.85 GAA (0.38) GAALMNAKDM4ERECQL
SCHEMBL11525071 0.83 GAA (0.37) GAALMNAKDM4ERECQL
SCHEMBL8211292 0.83 GAA (0.37) GAALMNAKDM4ERECQL
SCHEMBL11525229 0.79 GAA (0.35) GAA
SCHEMBL11051607 0.76 GAA (0.41) GAALMNARECQLALDH1A1MEN1
SCHEMBL11523500 0.75 GAA (0.50) GAALMNAKDM4EALDH1A1MEN1
SCHEMBL315320 0.75 GAA (0.50) GAALMNAKDM4EALDH1A1MEN1
SCHEMBL11289576 0.75 GAA (0.50) GAALMNAKDM4EALDH1A1MEN1
SCHEMBL6663050 0.74 GAA (0.40) GAARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0953595-A1 UV light stabilized polyester molding composition HOECHST CELANESE CORPORATION (US) 1999-11-03 EP claimed
EP-1097066-B1 LOAD LIMITING WEBBING ALLIED SIGNAL INC (US) 2004-08-04 EP disclosed
EP-1097066-A1 LOAD LIMITING WEBBING AlliedSignal Inc. (US) 2001-05-09 EP disclosed
US-6071835-A Load limiting webbing ALLIEDSIGNAL INC. (US) 2000-06-06 US disclosed
WO-1999065741-A1 LOAD LIMITING WEBBING ALLIEDSIGNAL INC. (US) 1999-12-23 WO disclosed
EP-0487485-A2 Weather-resistant powder coating compositions U C B, S.A. (BE) 1992-05-27 EP disclosed
US-5097006-A Polyesters U C B S.A. (BE) 1992-03-17 US disclosed
US-4525504-A 1,4-CYCLOHEXANDEICARBOXYLIC ACID AND 2,2,4,4-TETRAMETHYL-1,3-CYCLOBUTANEDIOL, UV AND HINDERED AMINE STABILIZERS EASTMAN KODAK COMPANY (US) 1985-06-25 US disclosed
US-4524165-A 1,4-CYCLOHEXANEDICARBOXYLIC ACID AND 1,4-CYCLOHEXANE DIOL MONOMERS; POLYALKYLENE GLCOLS; STABILIZER MIXTURE EASTMAN KODAK COMPANY (US) 1985-06-18 US disclosed