Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | ACP3 | P15309 | 4/20 | 0.45 |
| ▸ | ANPEP | P15144 | 4/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 3/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | PGK2 | P07205 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6661372 | 0.90 | HRH1 (0.52) | HRH1SRCACP3ANPEPERAP1 | |
| SCHEMBL6661377 | 0.90 | HRH1 (0.52) | HRH1SRCACP3ANPEPERAP1 | |
| SCHEMBL8733520 | 0.87 | HRH1 (0.44) | HRH1SRCACP3ANPEPERAP1 | |
| SCHEMBL8733506 | 0.87 | HRH1 (0.44) | HRH1SRCACP3ANPEPERAP1 | |
| SCHEMBL6665209 | 0.85 | SRC (0.50) | SRCACP3ANPEPHTR2ALAP3 | |
| SCHEMBL6664240 | 0.79 | HRH1 (0.46) | HRH1ACP3HTR2ALAP3 | |
| Phosphoric Acid SCHEMBL27396880 | 0.77 | HRH1 (0.75) | HRH1SRCACP3ANPEPERAP1 | |
| SCHEMBL6665280 | 0.77 | ANPEP (0.43) | SRCACP3ANPEPHTR2ALAP3 | |
| SCHEMBL5223505 | 0.70 | HRH1 (0.47) | HRH1SRCACP3HTR2ACYP2D6 | |
| SCHEMBL6661785 | 0.70 | HRH1 (0.49) | HRH1ACP3HTR2ALAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877028-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 1-AMINOPHOSPHONIC ACID DERIVATIVES AND NOVEL PHOSPHONATE COMPOUNDS | HOKKO CHEM IND CO (JP) | 2004-08-25 | — | — | EP | disclosed |