Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | NOS2 | P35228 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29025201 | 0.86 | SRC (0.44) | SLC6A2SLC6A4SLC6A3SRCNOS2 | |
| SCHEMBL8435976 | 0.80 | SMPD1 (0.45) | SRCPOLB | |
| SCHEMBL6908912 | 0.79 | ALDH1A1 (0.45) | SRCPOLBACP3 | |
| SCHEMBL3083466 | 0.79 | CYP2C19 (0.39) | SRCCYP2D6POLBACP3 | |
| SCHEMBL4943611 | 0.79 | SMPD1 (0.51) | POLB | |
| SCHEMBL28370463 | 0.79 | SRC (0.44) | SRCCYP2D6POLBACP3 | |
| SCHEMBL759322 | 0.79 | POLB (0.46) | SRCPOLBACP3 | |
| SCHEMBL28980053 | 0.79 | POLB (0.46) | SRCPOLBACP3 | |
| SCHEMBL15641732 | 0.78 | CYP1A2 (0.45) | SLC6A3SRCCYP2D6ACP3 | |
| SCHEMBL8517444 | 0.78 | S1PR2 (0.54) | CYP2D6ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824468-A2 | GLYCOGEN SYNTHASE KINASE-3 INHIBITORS | Tel Aviv University Future Technology Development L.P. (IL) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006054298-A2 | GLYCOGEN SYNTHASE KINASE-3 INHIBITORS | TEL AVIV UNIVERSITY FUTURE TECHNOLOGY DEVELOPMENT L.P. (IL) | 2006-05-26 | — | — | WO | disclosed |