Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5710443 | 0.89 | P2RX7 (0.75) | P2RX7 | |
| SCHEMBL5710583 | 0.88 | P2RX7 (0.68) | P2RX7 | |
| SCHEMBL5710693 | 0.88 | P2RX7 (0.68) | P2RX7 | |
| Hydrochloric Acid SCHEMBL5710531 | 0.87 | P2RX7 (0.67) | P2RX7 | |
| SCHEMBL5710475 | 0.86 | P2RX7 (0.68) | P2RX7 | |
| SCHEMBL4881659 | 0.86 | P2RX7 (0.67) | P2RX7 | |
| Hydrochloric Acid SCHEMBL5710644 | 0.85 | P2RX7 (0.70) | P2RX7 | |
| Hydrochloric Acid SCHEMBL5710674 | 0.85 | P2RX7 (0.67) | P2RX7 | |
| Hydrochloric Acid SCHEMBL5710713 | 0.85 | P2RX7 (0.67) | P2RX7 | |
| SCHEMBL5077420 | 0.84 | P2RX7 (0.66) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585640-B | N-adamantylmethyl derivates and intermediates as pharmaceutical compositions and processes for their preparation | ASTRAZENECA AB | 2010-10-27 | — | — | CN | disclosed |
| CN-1585640-A | N-adamantylmethyl derivates and intermediates as pharmaceutical compositions and processes for their preparation | ASTRAZENECA AB (SE) | 2005-02-23 | — | — | CN | disclosed |
| EP-1448195-A1 | N-ADAMANTYLMETHYL DERIVATES AND INTERMEDIATES AS PHARMACEUTICAL COMPOSITIONS AND PROCESSES FOR THEIR PREPARATION | AstraZeneca AB (SE) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003041707-A1 | N-ADAMANTYLMETHYL DERIVATES AND INTERMEDIATES AS PHARMACEUTICAL COMPOSITIONS AND PROCESSES FOR THEIR PREPARATION | ASTRAZENECA AB (SE) | 2003-05-22 | — | — | WO | disclosed |